Synthesis of a new class of β-iodo N-alkenyl 2-pyridones

Sarah Z. Tasker, Benjamin M. Brandsen, Keun Ah Ryu, Gregory S. Snapper, Richard J. Staples, Roger L. Dekock, Carolyn E. Anderson

Research output: Contribution to journalArticlepeer-review

Abstract

A new method for the synthesis of β-iodo N-alkenyl 2-pyridones from substituted 2-propargyloxypyridines has been discovered. These compounds present a unique complement of orthogonal functionality and structural characteristics that are unavailable via other routes. The ready access to these compounds renders them an important entry point for the preparation of more complex N-alkyl pyridone-containing targets.

Original languageEnglish (US)
Pages (from-to)6224-6227
Number of pages4
JournalOrganic Letters
Volume13
Issue number23
DOIs
StatePublished - Dec 2 2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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