The dawn phenomenon, an early morning glucose rise: Implications for diabetic intraday blood glucose variation

M. I. Schmidt, A. Hadji-Georgopoulos, M. Rendell, S. Margolis, A. Kowarski

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Abstract

Eleven insulin-dependent (type I) diabetic subjects were studied during a 24-h period to assess intraday blood glucose (BG) variation and related free insulin (FI) levels. Ten patients exhibited the dawn phenomenon, a rise in early morning fasting blood glucose (123 ± 81.1 m/dl; mean ± SD). This increase was positively and significantly correlated with the morning postprandial BG peak (r=0.723; P=0.012). FI/BG ratios were highest during the night (0.717 and 0.666 at 2200 and 0400 h, respectively) and lowest during the early morning (0.294 at 0800 h) (P

Original languageEnglish
Pages (from-to)579-585
Number of pages7
JournalDiabetes Care
Volume4
Issue number6
StatePublished - 1981
Externally publishedYes

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Blood Glucose
Glucose
Insulin
Fasting

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

Cite this

Schmidt, M. I., Hadji-Georgopoulos, A., Rendell, M., Margolis, S., & Kowarski, A. (1981). The dawn phenomenon, an early morning glucose rise: Implications for diabetic intraday blood glucose variation. Diabetes Care, 4(6), 579-585.

The dawn phenomenon, an early morning glucose rise : Implications for diabetic intraday blood glucose variation. / Schmidt, M. I.; Hadji-Georgopoulos, A.; Rendell, M.; Margolis, S.; Kowarski, A.

In: Diabetes Care, Vol. 4, No. 6, 1981, p. 579-585.

Research output: Contribution to journalArticle

Schmidt, MI, Hadji-Georgopoulos, A, Rendell, M, Margolis, S & Kowarski, A 1981, 'The dawn phenomenon, an early morning glucose rise: Implications for diabetic intraday blood glucose variation', Diabetes Care, vol. 4, no. 6, pp. 579-585.
Schmidt MI, Hadji-Georgopoulos A, Rendell M, Margolis S, Kowarski A. The dawn phenomenon, an early morning glucose rise: Implications for diabetic intraday blood glucose variation. Diabetes Care. 1981;4(6):579-585.
Schmidt, M. I. ; Hadji-Georgopoulos, A. ; Rendell, M. ; Margolis, S. ; Kowarski, A. / The dawn phenomenon, an early morning glucose rise : Implications for diabetic intraday blood glucose variation. In: Diabetes Care. 1981 ; Vol. 4, No. 6. pp. 579-585.
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