The Delphi and GRADE methodology used in the PSOGI 2018 consensus statement on Pseudomyxoma Peritonei and Peritoneal Mesothelioma

List of PSOGI collaborators

Research output: Contribution to journalReview article

Abstract

Pseudomyxoma Peritonei (PMP) and Peritoneal Mesothelioma (PM) are both rare peritoneal malignancies. Currently, affected patients may be treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy offering long-term survival or even cure in selected patients. However, many issues regarding the optimal treatment strategy are currently under debate. To aid physicians involved in the treatment of these patients in clinical decision making, the PSOGI executive committee proposed to create a consensus statement on PMP and PM. This manuscript describes the methodology of the consensus process. The Delphi technique is a reliable method for attaining consensus on a topic that lacks scientific evidence through multiple voting rounds which feeds back responses to the participants in between rounds. The GRADE system provides a structured framework for presenting and grading the available evidence. Separate questionnaires were created for PMP and PM and sent during two voting rounds to 80 and 38 experts, respectively. A consensus threshold of 51.0% was chosen. After the second round, consensus was reached on 92.9%–100.0% of the questions. The results were presented and discussed in the plenary session at the PSOGI 2018 international meeting in Paris. A third round for the remaining issues is currently in progress. In conclusion, using the Delphi technique and GRADE methodology, consensus was reached in many issues regarding the treatment of PM and PMP amongst an international panel of experts. The main results will be published in the near future.

Original languageEnglish (US)
JournalEuropean Journal of Surgical Oncology
DOIs
StatePublished - Jan 1 2019

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Pseudomyxoma Peritonei
Mesothelioma
Delphi Technique
Politics
Paris
Therapeutics
Physicians
Drug Therapy
Survival
Neoplasms

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oncology

Cite this

@article{5197c9b6f28e44b1a636473e8612e38a,
title = "The Delphi and GRADE methodology used in the PSOGI 2018 consensus statement on Pseudomyxoma Peritonei and Peritoneal Mesothelioma",
abstract = "Pseudomyxoma Peritonei (PMP) and Peritoneal Mesothelioma (PM) are both rare peritoneal malignancies. Currently, affected patients may be treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy offering long-term survival or even cure in selected patients. However, many issues regarding the optimal treatment strategy are currently under debate. To aid physicians involved in the treatment of these patients in clinical decision making, the PSOGI executive committee proposed to create a consensus statement on PMP and PM. This manuscript describes the methodology of the consensus process. The Delphi technique is a reliable method for attaining consensus on a topic that lacks scientific evidence through multiple voting rounds which feeds back responses to the participants in between rounds. The GRADE system provides a structured framework for presenting and grading the available evidence. Separate questionnaires were created for PMP and PM and sent during two voting rounds to 80 and 38 experts, respectively. A consensus threshold of 51.0{\%} was chosen. After the second round, consensus was reached on 92.9{\%}–100.0{\%} of the questions. The results were presented and discussed in the plenary session at the PSOGI 2018 international meeting in Paris. A third round for the remaining issues is currently in progress. In conclusion, using the Delphi technique and GRADE methodology, consensus was reached in many issues regarding the treatment of PM and PMP amongst an international panel of experts. The main results will be published in the near future.",
author = "{List of PSOGI collaborators} and Lurvink, {R. J.} and L. Villeneuve and K. Govaerts and {de Hingh}, {I. H.J.T.} and Moran, {B. J.} and M. Deraco and {Van der Speeten}, K. and O. Glehen and V. Kepenekian and S. Kusamura and Alyami, {Mohammad S.} and Thierry Andr{\'e} and Pedro Barrios-Sanchez and Baumgartner, {Joel M.} and Aditi Bhatt and Almog Ben-Yaacov and Rosella Bertulli and Jan Braess and Burger, {Jacobus W.A.} and Pedro Cascales-Campos and Peter Cashin and {Cecil, P}, Tom and Ceelen, {Wim P.} and Creemers, {Geert Jan} and Delia Cortes-Guiral and Sanjeev Dayal and {De Simone}, Michele and {Di Bartolomeo}, Maria and Pierre Dube and Kjersti Flatmark and Foster, {Jason M.} and Diane Goere and Luis Gonzales-Bayon and Alexander Heriot and Hewett, {Peter J.} and Hsieh, {Mao Chih} and Martin Hubner and Kok, {Niels F.M.} and Larsen, {Stein G.} and Kuno Lehmann and Yan Li and Loggie, {Brian W.} and Nicholas Lutton and Jasen Ly and Craig Lynch and Marcos Lyra and Sanket Mehta and Faheez Mohamed and Morris, {David L.} and Aviram Nissan",
year = "2019",
month = "1",
day = "1",
doi = "10.1016/j.ejso.2019.03.012",
language = "English (US)",
journal = "European Journal of Surgical Oncology",
issn = "0748-7983",
publisher = "W.B. Saunders Ltd",

}

TY - JOUR

T1 - The Delphi and GRADE methodology used in the PSOGI 2018 consensus statement on Pseudomyxoma Peritonei and Peritoneal Mesothelioma

AU - List of PSOGI collaborators

AU - Lurvink, R. J.

AU - Villeneuve, L.

AU - Govaerts, K.

AU - de Hingh, I. H.J.T.

AU - Moran, B. J.

AU - Deraco, M.

AU - Van der Speeten, K.

AU - Glehen, O.

AU - Kepenekian, V.

AU - Kusamura, S.

AU - Alyami, Mohammad S.

AU - André, Thierry

AU - Barrios-Sanchez, Pedro

AU - Baumgartner, Joel M.

AU - Bhatt, Aditi

AU - Ben-Yaacov, Almog

AU - Bertulli, Rosella

AU - Braess, Jan

AU - Burger, Jacobus W.A.

AU - Cascales-Campos, Pedro

AU - Cashin, Peter

AU - Cecil, P, Tom

AU - Ceelen, Wim P.

AU - Creemers, Geert Jan

AU - Cortes-Guiral, Delia

AU - Dayal, Sanjeev

AU - De Simone, Michele

AU - Di Bartolomeo, Maria

AU - Dube, Pierre

AU - Flatmark, Kjersti

AU - Foster, Jason M.

AU - Goere, Diane

AU - Gonzales-Bayon, Luis

AU - Heriot, Alexander

AU - Hewett, Peter J.

AU - Hsieh, Mao Chih

AU - Hubner, Martin

AU - Kok, Niels F.M.

AU - Larsen, Stein G.

AU - Lehmann, Kuno

AU - Li, Yan

AU - Loggie, Brian W.

AU - Lutton, Nicholas

AU - Ly, Jasen

AU - Lynch, Craig

AU - Lyra, Marcos

AU - Mehta, Sanket

AU - Mohamed, Faheez

AU - Morris, David L.

AU - Nissan, Aviram

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Pseudomyxoma Peritonei (PMP) and Peritoneal Mesothelioma (PM) are both rare peritoneal malignancies. Currently, affected patients may be treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy offering long-term survival or even cure in selected patients. However, many issues regarding the optimal treatment strategy are currently under debate. To aid physicians involved in the treatment of these patients in clinical decision making, the PSOGI executive committee proposed to create a consensus statement on PMP and PM. This manuscript describes the methodology of the consensus process. The Delphi technique is a reliable method for attaining consensus on a topic that lacks scientific evidence through multiple voting rounds which feeds back responses to the participants in between rounds. The GRADE system provides a structured framework for presenting and grading the available evidence. Separate questionnaires were created for PMP and PM and sent during two voting rounds to 80 and 38 experts, respectively. A consensus threshold of 51.0% was chosen. After the second round, consensus was reached on 92.9%–100.0% of the questions. The results were presented and discussed in the plenary session at the PSOGI 2018 international meeting in Paris. A third round for the remaining issues is currently in progress. In conclusion, using the Delphi technique and GRADE methodology, consensus was reached in many issues regarding the treatment of PM and PMP amongst an international panel of experts. The main results will be published in the near future.

AB - Pseudomyxoma Peritonei (PMP) and Peritoneal Mesothelioma (PM) are both rare peritoneal malignancies. Currently, affected patients may be treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy offering long-term survival or even cure in selected patients. However, many issues regarding the optimal treatment strategy are currently under debate. To aid physicians involved in the treatment of these patients in clinical decision making, the PSOGI executive committee proposed to create a consensus statement on PMP and PM. This manuscript describes the methodology of the consensus process. The Delphi technique is a reliable method for attaining consensus on a topic that lacks scientific evidence through multiple voting rounds which feeds back responses to the participants in between rounds. The GRADE system provides a structured framework for presenting and grading the available evidence. Separate questionnaires were created for PMP and PM and sent during two voting rounds to 80 and 38 experts, respectively. A consensus threshold of 51.0% was chosen. After the second round, consensus was reached on 92.9%–100.0% of the questions. The results were presented and discussed in the plenary session at the PSOGI 2018 international meeting in Paris. A third round for the remaining issues is currently in progress. In conclusion, using the Delphi technique and GRADE methodology, consensus was reached in many issues regarding the treatment of PM and PMP amongst an international panel of experts. The main results will be published in the near future.

UR - http://www.scopus.com/inward/record.url?scp=85063665130&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85063665130&partnerID=8YFLogxK

U2 - 10.1016/j.ejso.2019.03.012

DO - 10.1016/j.ejso.2019.03.012

M3 - Review article

AN - SCOPUS:85063665130

JO - European Journal of Surgical Oncology

JF - European Journal of Surgical Oncology

SN - 0748-7983

ER -