Abstract
Bronchial reactivity to inhaled methacholine exists in subjects with asthma but may occur in subjects with allergic rhinitis, chronic lung diseases, and during respiratory infections. In the absence of these factors, we found that age also has a significant effect on the methacholine response. One hundred forty-eight subjects, 5 to 76 years of age, were studied as normal control subjects in a natural history of asthma study. The methacholine response was measured by standard techniques. The analysis demonstrated that age had a significant effect on the methacholine response. In addition to known factors influencing the results of methacholine inhalation, young and older subjects may exhibit bronchial responses that may falsely suggest hyperreactive airway disease.
| Original language | English |
|---|---|
| Pages (from-to) | 609-613 |
| Number of pages | 5 |
| Journal | Journal of Allergy and Clinical Immunology |
| Volume | 76 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1985 |
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All Science Journal Classification (ASJC) codes
- Immunology
- Immunology and Allergy
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The effect of age on methacholine response. / Hopp, Russell J.; Bewtra, Againdra K.; Nair, Nicki M.; Townley, Robert G.
In: Journal of Allergy and Clinical Immunology, Vol. 76, No. 4, 1985, p. 609-613.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The effect of age on methacholine response
AU - Hopp, Russell J.
AU - Bewtra, Againdra K.
AU - Nair, Nicki M.
AU - Townley, Robert G.
PY - 1985
Y1 - 1985
N2 - Bronchial reactivity to inhaled methacholine exists in subjects with asthma but may occur in subjects with allergic rhinitis, chronic lung diseases, and during respiratory infections. In the absence of these factors, we found that age also has a significant effect on the methacholine response. One hundred forty-eight subjects, 5 to 76 years of age, were studied as normal control subjects in a natural history of asthma study. The methacholine response was measured by standard techniques. The analysis demonstrated that age had a significant effect on the methacholine response. In addition to known factors influencing the results of methacholine inhalation, young and older subjects may exhibit bronchial responses that may falsely suggest hyperreactive airway disease.
AB - Bronchial reactivity to inhaled methacholine exists in subjects with asthma but may occur in subjects with allergic rhinitis, chronic lung diseases, and during respiratory infections. In the absence of these factors, we found that age also has a significant effect on the methacholine response. One hundred forty-eight subjects, 5 to 76 years of age, were studied as normal control subjects in a natural history of asthma study. The methacholine response was measured by standard techniques. The analysis demonstrated that age had a significant effect on the methacholine response. In addition to known factors influencing the results of methacholine inhalation, young and older subjects may exhibit bronchial responses that may falsely suggest hyperreactive airway disease.
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UR - http://www.scopus.com/inward/citedby.url?scp=0021933763&partnerID=8YFLogxK
U2 - 10.1016/0091-6749(85)90783-3
DO - 10.1016/0091-6749(85)90783-3
M3 - Article
VL - 76
SP - 609
EP - 613
JO - Journal of Allergy and Clinical Immunology
JF - Journal of Allergy and Clinical Immunology
SN - 0091-6749
IS - 4
ER -