The effect of beta adrenergic blockade on bronchial sensitivity to acetyl-beta-methacholine in normal and allergic rhinitis subjects

Robert G. Townley; Steve McGeady; Againdra Bewtra

doi:10.1016/0091-6749(76)90093-2

The effect of beta adrenergic blockade on bronchial sensitivity to acetyl-beta-methacholine in normal and allergic rhinitis subjects

Robert G. Townley, Steve McGeady, Againdra Bewtra

Department of Medicine

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

The effect of propranolol inhalation on sensitivity to methacholine inhalation was studied in normal and allergic rhinitis subjects to determine whether beta adrenergic blockade alters sensitivity to mediators in nonasthmatic atopic individuals. A partial beta adrenergic blockade is suggested as being instrumental in asthma. Hay fever patients studied showed similar effects and also developed asthma for the first time.

Original language	English (US)
Pages (from-to)	358-366
Number of pages	9
Journal	The Journal of Allergy and Clinical Immunology
Volume	57
Issue number	4
DOIs	https://doi.org/10.1016/0091-6749(76)90093-2
State	Published - Apr 1976

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Immunology

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abstract = "The effect of propranolol inhalation on sensitivity to methacholine inhalation was studied in normal and allergic rhinitis subjects to determine whether beta adrenergic blockade alters sensitivity to mediators in nonasthmatic atopic individuals. A partial beta adrenergic blockade is suggested as being instrumental in asthma. Hay fever patients studied showed similar effects and also developed asthma for the first time.",

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