The effect of beta adrenergic blockade on bronchial sensitivity to acetyl-beta-methacholine in normal and allergic rhinitis subjects

Robert G. Townley, Steve McGeady, Againdra K. Bewtra

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Abstract

The effect of propranolol inhalation on sensitivity to methacholine inhalation was studied in normal and allergic rhinitis subjects to determine whether beta adrenergic blockade alters sensitivity to mediators in nonasthmatic atopic individuals. A partial beta adrenergic blockade is suggested as being instrumental in asthma. Hay fever patients studied showed similar effects and also developed asthma for the first time.

Original languageEnglish
Pages (from-to)358-366
Number of pages9
JournalJournal of Allergy and Clinical Immunology
Volume57
Issue number4
DOIs
StatePublished - 1976

Fingerprint

Methacholine Chloride
Adrenergic Agents
Inhalation
Asthma
Seasonal Allergic Rhinitis
Propranolol
Allergic Rhinitis

All Science Journal Classification (ASJC) codes

  • Immunology
  • Immunology and Allergy

Cite this

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abstract = "The effect of propranolol inhalation on sensitivity to methacholine inhalation was studied in normal and allergic rhinitis subjects to determine whether beta adrenergic blockade alters sensitivity to mediators in nonasthmatic atopic individuals. A partial beta adrenergic blockade is suggested as being instrumental in asthma. Hay fever patients studied showed similar effects and also developed asthma for the first time.",
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