Abstract
Background. It is undetermined whether calcium supplementation has an effect on obesity or body composition in postmenopausal women. The purpose of the study is to detect the effect of calcium supplementation on indices of obesity and body composition. Methods. This is a secondary analysis of data from a population-based, double-blind, placebo-controlled, randomized trial designed to determine the effects of calcium and vitamin D on osteoporotic fractures. The cohort included 1179 postmenopausal women who were randomly assigned into one of three groups: 1) supplemental calcium (1400 mg/d or 1500 mg/d) plus vitamin D placebo (Ca-only group); 2) supplemental calcium (1400 mg/d or 1500 mg/d) plus supplemental vitamin D3 (1100 IU/d) (Ca + D group); or, 3) two placebos (placebo group). After applying the exclusion criteria for this analysis, 870 subjects were included in this study. The primary outcomes for the present study were changes in body mass index, trunk fat, trunk lean, and percentage of trunk fat after calcium supplementation. Results. Changes in trunk fat, trunk lean, and percentage of trunk fat were significantly different between the calcium intervention groups (Ca-only group or Ca + D group) and the placebo group during the trial (P <0.05). The calcium intervention groups gained less trunk fat and maintained more trunk lean when compared to the placebo group. No significant difference was observed for body mass index between groups. Conclusion. Calcium supplementation over four years has a beneficial effect on body composition in postmenopausal women.
| Original language | English |
|---|---|
| Article number | 62 |
| Journal | Nutrition and Metabolism |
| Volume | 7 |
| DOIs | |
| State | Published - 2010 |
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All Science Journal Classification (ASJC) codes
- Medicine (miscellaneous)
- Nutrition and Dietetics
- Endocrinology, Diabetes and Metabolism
Cite this
The effect of calcium and vitamin D supplementation on obesity in postmenopausal women : Secondary analysis for a large-scale, placebo controlled, double-blind, 4-year longitudinal clinical trial. / Zhou, Jiapeng; Zhao, Lan Juan; Watson, Patrice; Zhang, Qin; Lappe, Joan M.
In: Nutrition and Metabolism, Vol. 7, 62, 2010.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The effect of calcium and vitamin D supplementation on obesity in postmenopausal women
T2 - Secondary analysis for a large-scale, placebo controlled, double-blind, 4-year longitudinal clinical trial
AU - Zhou, Jiapeng
AU - Zhao, Lan Juan
AU - Watson, Patrice
AU - Zhang, Qin
AU - Lappe, Joan M.
PY - 2010
Y1 - 2010
N2 - Background. It is undetermined whether calcium supplementation has an effect on obesity or body composition in postmenopausal women. The purpose of the study is to detect the effect of calcium supplementation on indices of obesity and body composition. Methods. This is a secondary analysis of data from a population-based, double-blind, placebo-controlled, randomized trial designed to determine the effects of calcium and vitamin D on osteoporotic fractures. The cohort included 1179 postmenopausal women who were randomly assigned into one of three groups: 1) supplemental calcium (1400 mg/d or 1500 mg/d) plus vitamin D placebo (Ca-only group); 2) supplemental calcium (1400 mg/d or 1500 mg/d) plus supplemental vitamin D3 (1100 IU/d) (Ca + D group); or, 3) two placebos (placebo group). After applying the exclusion criteria for this analysis, 870 subjects were included in this study. The primary outcomes for the present study were changes in body mass index, trunk fat, trunk lean, and percentage of trunk fat after calcium supplementation. Results. Changes in trunk fat, trunk lean, and percentage of trunk fat were significantly different between the calcium intervention groups (Ca-only group or Ca + D group) and the placebo group during the trial (P <0.05). The calcium intervention groups gained less trunk fat and maintained more trunk lean when compared to the placebo group. No significant difference was observed for body mass index between groups. Conclusion. Calcium supplementation over four years has a beneficial effect on body composition in postmenopausal women.
AB - Background. It is undetermined whether calcium supplementation has an effect on obesity or body composition in postmenopausal women. The purpose of the study is to detect the effect of calcium supplementation on indices of obesity and body composition. Methods. This is a secondary analysis of data from a population-based, double-blind, placebo-controlled, randomized trial designed to determine the effects of calcium and vitamin D on osteoporotic fractures. The cohort included 1179 postmenopausal women who were randomly assigned into one of three groups: 1) supplemental calcium (1400 mg/d or 1500 mg/d) plus vitamin D placebo (Ca-only group); 2) supplemental calcium (1400 mg/d or 1500 mg/d) plus supplemental vitamin D3 (1100 IU/d) (Ca + D group); or, 3) two placebos (placebo group). After applying the exclusion criteria for this analysis, 870 subjects were included in this study. The primary outcomes for the present study were changes in body mass index, trunk fat, trunk lean, and percentage of trunk fat after calcium supplementation. Results. Changes in trunk fat, trunk lean, and percentage of trunk fat were significantly different between the calcium intervention groups (Ca-only group or Ca + D group) and the placebo group during the trial (P <0.05). The calcium intervention groups gained less trunk fat and maintained more trunk lean when compared to the placebo group. No significant difference was observed for body mass index between groups. Conclusion. Calcium supplementation over four years has a beneficial effect on body composition in postmenopausal women.
UR - http://www.scopus.com/inward/record.url?scp=77954795700&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77954795700&partnerID=8YFLogxK
U2 - 10.1186/1743-7075-7-62
DO - 10.1186/1743-7075-7-62
M3 - Article
C2 - 20650013
AN - SCOPUS:77954795700
VL - 7
JO - Nutrition and Metabolism
JF - Nutrition and Metabolism
SN - 1743-7075
M1 - 62
ER -