Abstract
Sequential measurements of metacarpal cortical thickness show that premenopausal women as a group neither gain nor lose bone but that postmenopausal women (whether after artificial or natural menopause) lose approximately 1% per annum. Significantly reduced loss was observed with oestrogen therapy. There is no correlation between the rate of loss and dietary calcium in subjects on normal diets but the rate in those subjects on low calcium diets was significantly faster than in 12 subjects on calcium supplements. In postmenopausal women with spinal osteoporosis the rate of bone loss is more than twice that of the controls. This rate of loss is significantly reduced by treatment with large doses of vitamin D. The effectiveness of vitamin D therapy is related to the effect of the therapy on calcium absorption.
| Original language | English |
|---|---|
| Journal | BONE MINERAL DETERMINATIONS |
| State | Published - 1974 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
Cite this
The effect of therapy on sequential bone measurements in osteoporosis. / Nordin, B. E C; Horsman, A.; Gallagher, John Christopher G.
In: BONE MINERAL DETERMINATIONS, 1974.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The effect of therapy on sequential bone measurements in osteoporosis
AU - Nordin, B. E C
AU - Horsman, A.
AU - Gallagher, John Christopher G.
PY - 1974
Y1 - 1974
N2 - Sequential measurements of metacarpal cortical thickness show that premenopausal women as a group neither gain nor lose bone but that postmenopausal women (whether after artificial or natural menopause) lose approximately 1% per annum. Significantly reduced loss was observed with oestrogen therapy. There is no correlation between the rate of loss and dietary calcium in subjects on normal diets but the rate in those subjects on low calcium diets was significantly faster than in 12 subjects on calcium supplements. In postmenopausal women with spinal osteoporosis the rate of bone loss is more than twice that of the controls. This rate of loss is significantly reduced by treatment with large doses of vitamin D. The effectiveness of vitamin D therapy is related to the effect of the therapy on calcium absorption.
AB - Sequential measurements of metacarpal cortical thickness show that premenopausal women as a group neither gain nor lose bone but that postmenopausal women (whether after artificial or natural menopause) lose approximately 1% per annum. Significantly reduced loss was observed with oestrogen therapy. There is no correlation between the rate of loss and dietary calcium in subjects on normal diets but the rate in those subjects on low calcium diets was significantly faster than in 12 subjects on calcium supplements. In postmenopausal women with spinal osteoporosis the rate of bone loss is more than twice that of the controls. This rate of loss is significantly reduced by treatment with large doses of vitamin D. The effectiveness of vitamin D therapy is related to the effect of the therapy on calcium absorption.
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UR - http://www.scopus.com/inward/citedby.url?scp=0016149171&partnerID=8YFLogxK
M3 - Article
JO - BONE MINERAL DETERMINATIONS
JF - BONE MINERAL DETERMINATIONS
ER -