The expression patterns of c-kit and Sl in the chicken embryos suggest unexpected roles for these genes in somite and limb development

Mark Reedy, Randy L. Johnson, Carol A. Erickson

Research output: Contribution to journalReview article

19 Citations (Scopus)

Abstract

We have used whole-mount in situ hybridization to investigate the patterns of c-kit and Sl expression in stage 11-22 chicken embryos. Our analysis shows that c-kit and Sl are expressed quite differently in chicken embryos compared to the reported expression patterns of these genes in embryos of other taxa. Most notably, chicken c-kit is expressed in primordial germ cells as well as in the developing somite, the apical ectodermal ridge, and in the early foregut endoderm. Sl is expressed in the lateral and intermediate mesoderm and in extraembryonic membranes. These data suggest that chicken c-kit and Sl may play novel and unexpected roles in somitogenesis, limb development, and foregut development in avian embryos.

Original languageEnglish
Pages (from-to)53-58
Number of pages6
JournalGene Expression Patterns
Volume3
Issue number1
DOIs
StatePublished - Mar 2003

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Somites
Chickens
Embryonic Structures
Extremities
Genes
Extraembryonic Membranes
Endoderm
Mesoderm
Germ Cells
In Situ Hybridization
Gene Expression

All Science Journal Classification (ASJC) codes

  • Genetics
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Developmental Neuroscience

Cite this

The expression patterns of c-kit and Sl in the chicken embryos suggest unexpected roles for these genes in somite and limb development. / Reedy, Mark; Johnson, Randy L.; Erickson, Carol A.

In: Gene Expression Patterns, Vol. 3, No. 1, 03.2003, p. 53-58.

Research output: Contribution to journalReview article

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