Abstract
We have used whole-mount in situ hybridization to investigate the patterns of c-kit and Sl expression in stage 11-22 chicken embryos. Our analysis shows that c-kit and Sl are expressed quite differently in chicken embryos compared to the reported expression patterns of these genes in embryos of other taxa. Most notably, chicken c-kit is expressed in primordial germ cells as well as in the developing somite, the apical ectodermal ridge, and in the early foregut endoderm. Sl is expressed in the lateral and intermediate mesoderm and in extraembryonic membranes. These data suggest that chicken c-kit and Sl may play novel and unexpected roles in somitogenesis, limb development, and foregut development in avian embryos.
| Original language | English |
|---|---|
| Pages (from-to) | 53-58 |
| Number of pages | 6 |
| Journal | Gene Expression Patterns |
| Volume | 3 |
| Issue number | 1 |
| DOIs | |
| State | Published - Mar 2003 |
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All Science Journal Classification (ASJC) codes
- Genetics
- Molecular Biology
- Cellular and Molecular Neuroscience
- Developmental Neuroscience
Cite this
The expression patterns of c-kit and Sl in the chicken embryos suggest unexpected roles for these genes in somite and limb development. / Reedy, Mark; Johnson, Randy L.; Erickson, Carol A.
In: Gene Expression Patterns, Vol. 3, No. 1, 03.2003, p. 53-58.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - The expression patterns of c-kit and Sl in the chicken embryos suggest unexpected roles for these genes in somite and limb development
AU - Reedy, Mark
AU - Johnson, Randy L.
AU - Erickson, Carol A.
PY - 2003/3
Y1 - 2003/3
N2 - We have used whole-mount in situ hybridization to investigate the patterns of c-kit and Sl expression in stage 11-22 chicken embryos. Our analysis shows that c-kit and Sl are expressed quite differently in chicken embryos compared to the reported expression patterns of these genes in embryos of other taxa. Most notably, chicken c-kit is expressed in primordial germ cells as well as in the developing somite, the apical ectodermal ridge, and in the early foregut endoderm. Sl is expressed in the lateral and intermediate mesoderm and in extraembryonic membranes. These data suggest that chicken c-kit and Sl may play novel and unexpected roles in somitogenesis, limb development, and foregut development in avian embryos.
AB - We have used whole-mount in situ hybridization to investigate the patterns of c-kit and Sl expression in stage 11-22 chicken embryos. Our analysis shows that c-kit and Sl are expressed quite differently in chicken embryos compared to the reported expression patterns of these genes in embryos of other taxa. Most notably, chicken c-kit is expressed in primordial germ cells as well as in the developing somite, the apical ectodermal ridge, and in the early foregut endoderm. Sl is expressed in the lateral and intermediate mesoderm and in extraembryonic membranes. These data suggest that chicken c-kit and Sl may play novel and unexpected roles in somitogenesis, limb development, and foregut development in avian embryos.
UR - http://www.scopus.com/inward/record.url?scp=0037347488&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037347488&partnerID=8YFLogxK
U2 - 10.1016/S1567-133X(02)00072-8
DO - 10.1016/S1567-133X(02)00072-8
M3 - Review article
C2 - 12609603
AN - SCOPUS:0037347488
VL - 3
SP - 53
EP - 58
JO - Gene Expression Patterns
JF - Gene Expression Patterns
SN - 1567-133X
IS - 1
ER -