Abstract
Male breast carcinoma shares many similar epidemiologic, genetic, diagnostic, therapeutic, and prognostic factors with breast carcinoma in women. The genetic factor most clearly associated with male breast carcinoma is the BRCA2 germ-line mutation. Other heritable mutations observed in male breast carcinoma include BRCA1, the androgen receptor gene, and the mismatch repair genes associated with Lynch syndrome.
| Original language | English |
|---|---|
| Pages (from-to) | 744-746 |
| Number of pages | 3 |
| Journal | Cancer |
| Volume | 86 |
| Issue number | 5 |
| DOIs | |
| State | Published - Sep 1 1999 |
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All Science Journal Classification (ASJC) codes
- Cancer Research
- Oncology
Cite this
The genetic epidemiology of male breast carcinoma. / Lynch, Henry T.; Watson, P.; Narod, S. A.
In: Cancer, Vol. 86, No. 5, 01.09.1999, p. 744-746.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - The genetic epidemiology of male breast carcinoma
AU - Lynch, Henry T.
AU - Watson, P.
AU - Narod, S. A.
PY - 1999/9/1
Y1 - 1999/9/1
N2 - Male breast carcinoma shares many similar epidemiologic, genetic, diagnostic, therapeutic, and prognostic factors with breast carcinoma in women. The genetic factor most clearly associated with male breast carcinoma is the BRCA2 germ-line mutation. Other heritable mutations observed in male breast carcinoma include BRCA1, the androgen receptor gene, and the mismatch repair genes associated with Lynch syndrome.
AB - Male breast carcinoma shares many similar epidemiologic, genetic, diagnostic, therapeutic, and prognostic factors with breast carcinoma in women. The genetic factor most clearly associated with male breast carcinoma is the BRCA2 germ-line mutation. Other heritable mutations observed in male breast carcinoma include BRCA1, the androgen receptor gene, and the mismatch repair genes associated with Lynch syndrome.
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UR - http://www.scopus.com/inward/citedby.url?scp=0033198067&partnerID=8YFLogxK
U2 - 10.1002/(SICI)1097-0142(19990901)86:5<744::AID-CNCR4>3.0.CO;2-G
DO - 10.1002/(SICI)1097-0142(19990901)86:5<744::AID-CNCR4>3.0.CO;2-G
M3 - Review article
C2 - 10463967
AN - SCOPUS:0033198067
VL - 86
SP - 744
EP - 746
JO - Cancer
JF - Cancer
SN - 0008-543X
IS - 5
ER -