The genetic epidemiology of male breast carcinoma

H. T. Lynch; P. Watson; S. A. Narod

doi:10.1002/(SICI)1097-0142(19990901)86:5<744::AID-CNCR4>3.0.CO;2-G

The genetic epidemiology of male breast carcinoma

H. T. Lynch, P. Watson, S. A. Narod

Department of Preventive Medicine

Research output: Contribution to journal › Review article › peer-review

32 Scopus citations

Abstract

Male breast carcinoma shares many similar epidemiologic, genetic, diagnostic, therapeutic, and prognostic factors with breast carcinoma in women. The genetic factor most clearly associated with male breast carcinoma is the BRCA2 germ-line mutation. Other heritable mutations observed in male breast carcinoma include BRCA1, the androgen receptor gene, and the mismatch repair genes associated with Lynch syndrome.

Original language	English (US)
Pages (from-to)	744-746
Number of pages	3
Journal	Cancer
Volume	86
Issue number	5
DOIs	https://doi.org/10.1002/(SICI)1097-0142(19990901)86:5<744::AID-CNCR4>3.0.CO;2-G
State	Published - Sep 1 1999

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

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10.1002/(SICI)1097-0142(19990901)86:5<744::AID-CNCR4>3.0.CO;2-G

Cite this

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AB - Male breast carcinoma shares many similar epidemiologic, genetic, diagnostic, therapeutic, and prognostic factors with breast carcinoma in women. The genetic factor most clearly associated with male breast carcinoma is the BRCA2 germ-line mutation. Other heritable mutations observed in male breast carcinoma include BRCA1, the androgen receptor gene, and the mismatch repair genes associated with Lynch syndrome.

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The genetic epidemiology of male breast carcinoma

Abstract

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