Abstract
One of the most daunting concerns in modern health care today is the issue of nosocomial infection and associated efforts to monitor and control it. Over the years, the epidemiological analysis of nosocomial infection has undergone a remarkable evolutionary metamorphosis. While initially relying on purely phenotypic characterization, recent years have seen a variety of approaches to epidemiological analysis emerge from developments in molecular biology, resulting in the advent of what is conventionally termed 'molecular epidemiology'. The chronology of that process is reviewed here, considering the advantages and disadvantages of the various typing methods, concentrating especially on the most widely used current approaches. In addition, issues related to when one should use molecular typing, specific approaches to use, application scenarios, and possible future developments are also addressed. (C) 2000 Lippincott Williams and Wilkins.
| Original language | English |
|---|---|
| Pages (from-to) | 145-152 |
| Number of pages | 8 |
| Journal | Reviews in Medical Microbiology |
| Volume | 11 |
| Issue number | 3 |
| State | Published - 2000 |
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All Science Journal Classification (ASJC) codes
- Microbiology
- Microbiology (medical)
Cite this
The molecular epidemiology of nosocomial infection : Past, present and future. / Goering, Richard V.
In: Reviews in Medical Microbiology, Vol. 11, No. 3, 2000, p. 145-152.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - The molecular epidemiology of nosocomial infection
T2 - Past, present and future
AU - Goering, Richard V.
PY - 2000
Y1 - 2000
N2 - One of the most daunting concerns in modern health care today is the issue of nosocomial infection and associated efforts to monitor and control it. Over the years, the epidemiological analysis of nosocomial infection has undergone a remarkable evolutionary metamorphosis. While initially relying on purely phenotypic characterization, recent years have seen a variety of approaches to epidemiological analysis emerge from developments in molecular biology, resulting in the advent of what is conventionally termed 'molecular epidemiology'. The chronology of that process is reviewed here, considering the advantages and disadvantages of the various typing methods, concentrating especially on the most widely used current approaches. In addition, issues related to when one should use molecular typing, specific approaches to use, application scenarios, and possible future developments are also addressed. (C) 2000 Lippincott Williams and Wilkins.
AB - One of the most daunting concerns in modern health care today is the issue of nosocomial infection and associated efforts to monitor and control it. Over the years, the epidemiological analysis of nosocomial infection has undergone a remarkable evolutionary metamorphosis. While initially relying on purely phenotypic characterization, recent years have seen a variety of approaches to epidemiological analysis emerge from developments in molecular biology, resulting in the advent of what is conventionally termed 'molecular epidemiology'. The chronology of that process is reviewed here, considering the advantages and disadvantages of the various typing methods, concentrating especially on the most widely used current approaches. In addition, issues related to when one should use molecular typing, specific approaches to use, application scenarios, and possible future developments are also addressed. (C) 2000 Lippincott Williams and Wilkins.
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UR - http://www.scopus.com/inward/citedby.url?scp=0033636077&partnerID=8YFLogxK
M3 - Review article
VL - 11
SP - 145
EP - 152
JO - Reviews in Medical Microbiology
JF - Reviews in Medical Microbiology
SN - 0954-139X
IS - 3
ER -