The relationship between large cavum septum pellucidum and antisocial behavior, callous-unemotional traits and psychopathy in adolescents

Stuart F. White, Sarah Brislin, Stephen Sinclair, Katherine A. Fowler, Kayla Pope, R. James R Blair

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Background: The presence of a large cavum septum pellucidum (CSP) has been previously associated with antisocial behavior/psychopathic traits in an adult community sample. Aims: The current study investigated the relationship between a large CSP and symptom severity in disruptive behavior disorders (DBD; conduct disorder and oppositional defiant disorder). Method: Structural MRI scans of youth with DBDs (N = 32) and healthy comparison youth (N = 27) were examined for the presence of a large CSP and if this was related to symptom severity. Results: Replicating previous results, a large CSP was associated with DBD diagnosis, proactive aggression, and level of psychopathic traits in youth. However, the presence of a large CSP was unrelated to aggression or psychopathic traits within the DBD sample. Conclusions: Early brain mal-development may increase the risk of a DBD diagnosis, but does not mark a particularly severe form of DBD within patients receiving these diagnoses.

Original languageEnglish (US)
Pages (from-to)575-581
Number of pages7
JournalJournal of Child Psychology and Psychiatry and Allied Disciplines
Volume54
Issue number5
DOIs
StatePublished - May 1 2013
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health
  • Pediatrics, Perinatology, and Child Health
  • Developmental and Educational Psychology
  • Medicine(all)

Fingerprint Dive into the research topics of 'The relationship between large cavum septum pellucidum and antisocial behavior, callous-unemotional traits and psychopathy in adolescents'. Together they form a unique fingerprint.

  • Cite this