The role of calcium intake in preventing bone fragility, hypertension, and certain cancers

M. J. Barger-Lux, R. P. Heaney

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

This paper examines the evidence that connects calcium intake and vitamin D status to bone fragility, hypertension, colon cancer, and breast cancer. Human calcium physiology, with an intestinal absorptive barrier and inefficient conservation, reflects the abundance of calcium in the primordial human food supply. The calcium intake of stone-age adults is estimated at 50 to 75 mmol/d, three to five times the median calcium intake of present-day U.S. adults. Long-term calcium restriction and/or insufficient vitamin D may promote the development of bone fragility, high blood pressure, colon cancer, and breast cancer in susceptible individuals. Conversely, improvement in calcium intake and/or in vitamin D status may help to prevent these serious health problems. At least 12 intervention studies have established the skeletal benefit of increased calcium intake among women in the late postmenopause. Other reports suggest that adequate calcium may protect against salt-sensitive and pregnancy-associated hypertension. High intakes of both dietary calcium and vitamin D are associated with reduced development of precancerous changes in colonic mucosa. Preliminary findings also suggest that vitamin D has a protective effect against breast cancer.

Original languageEnglish
JournalJournal of Nutrition
Volume124
Issue number8 SUPPL.
StatePublished - 1994

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hypertension
bones
Hypertension
Calcium
calcium
Bone and Bones
neoplasms
Vitamin D
vitamin D
Neoplasms
Breast Neoplasms
breast neoplasms
Colonic Neoplasms
colorectal neoplasms
postmenopause
Postmenopause
Dietary Calcium
Food Supply
Bone Development
skeletal development

All Science Journal Classification (ASJC) codes

  • Food Science
  • Medicine (miscellaneous)

Cite this

The role of calcium intake in preventing bone fragility, hypertension, and certain cancers. / Barger-Lux, M. J.; Heaney, R. P.

In: Journal of Nutrition, Vol. 124, No. 8 SUPPL., 1994.

Research output: Contribution to journalArticle

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