Therapeutic ultrasound-enhanced thrombolysis in patients with acute myocardial infarction

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Thrombolytic therapy is widely used to treat the patients with ST elevation acute myocardial infarction (STE-MI). Due to logistic and economic reasons, only 10% of patients with acute myocardial infarction can be treated with the percutaneous coronary intervention (PCI). Optimal flow (TIMI (Thrombolysis In Myocardial Infarction) 3 flow) is achieved in only about 60% of cases by enzymatic thrombolysis. Therapeutic ultrasound (US) exerts an effect on thrombolysis by micromechanical processes or indirectly by supporting enzymatic thrombolysis. This review examines relevant experimental and clinical published data. Technical issues in therapeutic US-enhanced thrombolysis in patients with acute myocardial infarction and advancements of the techniques during recent 10 years are discussed.

Original languageEnglish
Pages (from-to)253-258
Number of pages6
JournalAngiology
Volume61
Issue number3
DOIs
StatePublished - Jun 2010

Fingerprint

Myocardial Infarction
Thrombolytic Therapy
Percutaneous Coronary Intervention
Therapeutics
Economics
ST Elevation Myocardial Infarction

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Therapeutic ultrasound-enhanced thrombolysis in patients with acute myocardial infarction. / Shen, Xuedong; Nair, Chandra; Holmberg, Mark Jeffrey; Mooss, Aryan N.; Arouni, Amy; Esterbrooks, Dennis J.

In: Angiology, Vol. 61, No. 3, 06.2010, p. 253-258.

Research output: Contribution to journalReview article

@article{2579b9975ea3450685d6b645c05f0232,
title = "Therapeutic ultrasound-enhanced thrombolysis in patients with acute myocardial infarction",
abstract = "Thrombolytic therapy is widely used to treat the patients with ST elevation acute myocardial infarction (STE-MI). Due to logistic and economic reasons, only 10{\%} of patients with acute myocardial infarction can be treated with the percutaneous coronary intervention (PCI). Optimal flow (TIMI (Thrombolysis In Myocardial Infarction) 3 flow) is achieved in only about 60{\%} of cases by enzymatic thrombolysis. Therapeutic ultrasound (US) exerts an effect on thrombolysis by micromechanical processes or indirectly by supporting enzymatic thrombolysis. This review examines relevant experimental and clinical published data. Technical issues in therapeutic US-enhanced thrombolysis in patients with acute myocardial infarction and advancements of the techniques during recent 10 years are discussed.",
author = "Xuedong Shen and Chandra Nair and Holmberg, {Mark Jeffrey} and Mooss, {Aryan N.} and Amy Arouni and Esterbrooks, {Dennis J.}",
year = "2010",
month = "6",
doi = "10.1177/0003319709343287",
language = "English",
volume = "61",
pages = "253--258",
journal = "Angiology",
issn = "0003-3197",
publisher = "SAGE Publications Inc.",
number = "3",

}

TY - JOUR

T1 - Therapeutic ultrasound-enhanced thrombolysis in patients with acute myocardial infarction

AU - Shen, Xuedong

AU - Nair, Chandra

AU - Holmberg, Mark Jeffrey

AU - Mooss, Aryan N.

AU - Arouni, Amy

AU - Esterbrooks, Dennis J.

PY - 2010/6

Y1 - 2010/6

N2 - Thrombolytic therapy is widely used to treat the patients with ST elevation acute myocardial infarction (STE-MI). Due to logistic and economic reasons, only 10% of patients with acute myocardial infarction can be treated with the percutaneous coronary intervention (PCI). Optimal flow (TIMI (Thrombolysis In Myocardial Infarction) 3 flow) is achieved in only about 60% of cases by enzymatic thrombolysis. Therapeutic ultrasound (US) exerts an effect on thrombolysis by micromechanical processes or indirectly by supporting enzymatic thrombolysis. This review examines relevant experimental and clinical published data. Technical issues in therapeutic US-enhanced thrombolysis in patients with acute myocardial infarction and advancements of the techniques during recent 10 years are discussed.

AB - Thrombolytic therapy is widely used to treat the patients with ST elevation acute myocardial infarction (STE-MI). Due to logistic and economic reasons, only 10% of patients with acute myocardial infarction can be treated with the percutaneous coronary intervention (PCI). Optimal flow (TIMI (Thrombolysis In Myocardial Infarction) 3 flow) is achieved in only about 60% of cases by enzymatic thrombolysis. Therapeutic ultrasound (US) exerts an effect on thrombolysis by micromechanical processes or indirectly by supporting enzymatic thrombolysis. This review examines relevant experimental and clinical published data. Technical issues in therapeutic US-enhanced thrombolysis in patients with acute myocardial infarction and advancements of the techniques during recent 10 years are discussed.

UR - http://www.scopus.com/inward/record.url?scp=77949879447&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77949879447&partnerID=8YFLogxK

U2 - 10.1177/0003319709343287

DO - 10.1177/0003319709343287

M3 - Review article

VL - 61

SP - 253

EP - 258

JO - Angiology

JF - Angiology

SN - 0003-3197

IS - 3

ER -