Transmembrane Ca2+ gradient and function of membrane proteins

F. Y. Yang, Y. G. Huang, Yaping Tu

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

This review will focus on the recent advance in the study of effect of transmembrane Ca2+ gradient on the function of membrane proteins. It consits of two parts: 1. Transmembrane Ca2+ gradient and sarcoplasmic reticulum Ca2+-ATPase; 2. Effect of transmembrane Ca2+ gradient on the components and coupling of cAMP signal transduction pathway. The results obtained indicate that a proper transmembrane Ca2+ gradient may play an important role in modulating the conformation and activity of SR Ca2+-ATPase and the function of membrane proteins involved in the cAMP signal transduction by mediating the physical state change of the membrane phospholipids.

Original languageEnglish
Pages (from-to)351-364
Number of pages14
JournalBioscience Reports
Volume15
Issue number5
DOIs
StatePublished - Oct 1995
Externally publishedYes

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Signal transduction
Calcium-Transporting ATPases
Signal Transduction
Membrane Proteins
Sarcoplasmic Reticulum
Conformations
Phospholipids
Membranes

All Science Journal Classification (ASJC) codes

  • Cell Biology
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Transmembrane Ca2+ gradient and function of membrane proteins. / Yang, F. Y.; Huang, Y. G.; Tu, Yaping.

In: Bioscience Reports, Vol. 15, No. 5, 10.1995, p. 351-364.

Research output: Contribution to journalReview article

Yang, F. Y. ; Huang, Y. G. ; Tu, Yaping. / Transmembrane Ca2+ gradient and function of membrane proteins. In: Bioscience Reports. 1995 ; Vol. 15, No. 5. pp. 351-364.
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