Abstract
This review will focus on the recent advance in the study of effect of transmembrane Ca2+ gradient on the function of membrane proteins. It consits of two parts: 1. Transmembrane Ca2+ gradient and sarcoplasmic reticulum Ca2+-ATPase; 2. Effect of transmembrane Ca2+ gradient on the components and coupling of cAMP signal transduction pathway. The results obtained indicate that a proper transmembrane Ca2+ gradient may play an important role in modulating the conformation and activity of SR Ca2+-ATPase and the function of membrane proteins involved in the cAMP signal transduction by mediating the physical state change of the membrane phospholipids.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 351-364 |
| Number of pages | 14 |
| Journal | Bioscience Reports |
| Volume | 15 |
| Issue number | 5 |
| DOIs | |
| State | Published - Oct 1 1995 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Biophysics
- Biochemistry
- Molecular Biology
- Cell Biology
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Yang, F. Y., Huang, Y. G., & Tu, Y. P. (1995). Transmembrane Ca2+ gradient and function of membrane proteins. Bioscience Reports, 15(5), 351-364. https://doi.org/10.1007/BF01788367