Transmembrane Ca2+ gradient and function of membrane proteins

F. Y. Yang; Y. G. Huang; Y. P. Tu

doi:10.1007/BF01788367

Transmembrane Ca²⁺ gradient and function of membrane proteins

F. Y. Yang, Y. G. Huang, Y. P. Tu

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

This review will focus on the recent advance in the study of effect of transmembrane Ca²⁺ gradient on the function of membrane proteins. It consits of two parts: 1. Transmembrane Ca²⁺ gradient and sarcoplasmic reticulum Ca²⁺-ATPase; 2. Effect of transmembrane Ca²⁺ gradient on the components and coupling of cAMP signal transduction pathway. The results obtained indicate that a proper transmembrane Ca²⁺ gradient may play an important role in modulating the conformation and activity of SR Ca²⁺-ATPase and the function of membrane proteins involved in the cAMP signal transduction by mediating the physical state change of the membrane phospholipids.

Original language	English (US)
Pages (from-to)	351-364
Number of pages	14
Journal	Bioscience Reports
Volume	15
Issue number	5
DOIs	https://doi.org/10.1007/BF01788367
State	Published - Oct 1 1995
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biophysics
Biochemistry
Molecular Biology
Cell Biology

Access to Document

10.1007/BF01788367

Fingerprint Dive into the research topics of 'Transmembrane Ca<sup>2+</sup> gradient and function of membrane proteins'. Together they form a unique fingerprint.

Cite this

@article{d2a7504f345448d68415e9d5dd4cf594,

title = "Transmembrane Ca2+ gradient and function of membrane proteins",

abstract = "This review will focus on the recent advance in the study of effect of transmembrane Ca2+ gradient on the function of membrane proteins. It consits of two parts: 1. Transmembrane Ca2+ gradient and sarcoplasmic reticulum Ca2+-ATPase; 2. Effect of transmembrane Ca2+ gradient on the components and coupling of cAMP signal transduction pathway. The results obtained indicate that a proper transmembrane Ca2+ gradient may play an important role in modulating the conformation and activity of SR Ca2+-ATPase and the function of membrane proteins involved in the cAMP signal transduction by mediating the physical state change of the membrane phospholipids.",

author = "Yang, {F. Y.} and Huang, {Y. G.} and Tu, {Y. P.}",

year = "1995",

month = oct,

day = "1",

doi = "10.1007/BF01788367",

language = "English (US)",

volume = "15",

pages = "351--364",

journal = "Bioscience Reports",

issn = "0144-8463",

publisher = "Portland Press Ltd.",

number = "5",

}

TY - JOUR

T1 - Transmembrane Ca2+ gradient and function of membrane proteins

AU - Yang, F. Y.

AU - Huang, Y. G.

AU - Tu, Y. P.

PY - 1995/10/1

Y1 - 1995/10/1

N2 - This review will focus on the recent advance in the study of effect of transmembrane Ca2+ gradient on the function of membrane proteins. It consits of two parts: 1. Transmembrane Ca2+ gradient and sarcoplasmic reticulum Ca2+-ATPase; 2. Effect of transmembrane Ca2+ gradient on the components and coupling of cAMP signal transduction pathway. The results obtained indicate that a proper transmembrane Ca2+ gradient may play an important role in modulating the conformation and activity of SR Ca2+-ATPase and the function of membrane proteins involved in the cAMP signal transduction by mediating the physical state change of the membrane phospholipids.

AB - This review will focus on the recent advance in the study of effect of transmembrane Ca2+ gradient on the function of membrane proteins. It consits of two parts: 1. Transmembrane Ca2+ gradient and sarcoplasmic reticulum Ca2+-ATPase; 2. Effect of transmembrane Ca2+ gradient on the components and coupling of cAMP signal transduction pathway. The results obtained indicate that a proper transmembrane Ca2+ gradient may play an important role in modulating the conformation and activity of SR Ca2+-ATPase and the function of membrane proteins involved in the cAMP signal transduction by mediating the physical state change of the membrane phospholipids.

UR - http://www.scopus.com/inward/record.url?scp=0029414783&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029414783&partnerID=8YFLogxK

U2 - 10.1007/BF01788367

DO - 10.1007/BF01788367

M3 - Review article

C2 - 8825037

AN - SCOPUS:0029414783

VL - 15

SP - 351

EP - 364

JO - Bioscience Reports

JF - Bioscience Reports

SN - 0144-8463

IS - 5

ER -