Transmembrane Ca2+ gradient and function of membrane proteins

F. Y. Yang; Y. G. Huang; Y. P. Tu

doi:10.1007/BF01788367

Transmembrane Ca²⁺ gradient and function of membrane proteins

F. Y. Yang, Y. G. Huang, Y. P. Tu

Research output: Contribution to journal › Review article

11 Scopus citations

Abstract

This review will focus on the recent advance in the study of effect of transmembrane Ca²⁺ gradient on the function of membrane proteins. It consits of two parts: 1. Transmembrane Ca²⁺ gradient and sarcoplasmic reticulum Ca²⁺-ATPase; 2. Effect of transmembrane Ca²⁺ gradient on the components and coupling of cAMP signal transduction pathway. The results obtained indicate that a proper transmembrane Ca²⁺ gradient may play an important role in modulating the conformation and activity of SR Ca²⁺-ATPase and the function of membrane proteins involved in the cAMP signal transduction by mediating the physical state change of the membrane phospholipids.

Original language	English (US)
Pages (from-to)	351-364
Number of pages	14
Journal	Bioscience Reports
Volume	15
Issue number	5
DOIs	https://doi.org/10.1007/BF01788367
State	Published - Oct 1 1995
Externally published	Yes

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All Science Journal Classification (ASJC) codes

Biophysics
Biochemistry
Molecular Biology
Cell Biology

Cite this

Yang, F. Y., Huang, Y. G., & Tu, Y. P. (1995). Transmembrane Ca²⁺ gradient and function of membrane proteins. Bioscience Reports, 15(5), 351-364. https://doi.org/10.1007/BF01788367

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10.1007/BF01788367