Abstract
In this article the regression tree method is extended to correlated survival data and applied to the problem of developing objective prognostic classification rules in periodontal research. The robust logrank statistic is used as the splitting statistic to measure the between-node difference in survival, while adjusting for correlation among failure times from the same patient. The partition-based survival function estimator is shown to converge to the true conditional survival function. Tooth loss data from 100 periodontal patients (2,509 teeth) was analyzed using the proposed method. The goal is to assign each tooth to one of the five prognosis categories (good, fair, poor, questionable, or hopeless). After the best-sized tree was identified, an amalgamation procedure was used to form five prognostic groups. The prognostic rules established here may be used by periodontists, general dentists, and insurance companies in devising appropriate treatment plans for periodontal oatients.
| Original language | English |
|---|---|
| Pages (from-to) | 959-967 |
| Number of pages | 9 |
| Journal | Journal of the American Statistical Association |
| Volume | 101 |
| Issue number | 475 |
| DOIs | |
| State | Published - Sep 2006 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Mathematics(all)
- Statistics and Probability
Cite this
Trees for correlated survival data by goodness of split, with applications to tooth prognosis. / Fan, Juanjuan; Su, Xiao Gang; Levine, Richard A.; Nunn, Martha E.; Leblanc, Michael.
In: Journal of the American Statistical Association, Vol. 101, No. 475, 09.2006, p. 959-967.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Trees for correlated survival data by goodness of split, with applications to tooth prognosis
AU - Fan, Juanjuan
AU - Su, Xiao Gang
AU - Levine, Richard A.
AU - Nunn, Martha E.
AU - Leblanc, Michael
PY - 2006/9
Y1 - 2006/9
N2 - In this article the regression tree method is extended to correlated survival data and applied to the problem of developing objective prognostic classification rules in periodontal research. The robust logrank statistic is used as the splitting statistic to measure the between-node difference in survival, while adjusting for correlation among failure times from the same patient. The partition-based survival function estimator is shown to converge to the true conditional survival function. Tooth loss data from 100 periodontal patients (2,509 teeth) was analyzed using the proposed method. The goal is to assign each tooth to one of the five prognosis categories (good, fair, poor, questionable, or hopeless). After the best-sized tree was identified, an amalgamation procedure was used to form five prognostic groups. The prognostic rules established here may be used by periodontists, general dentists, and insurance companies in devising appropriate treatment plans for periodontal oatients.
AB - In this article the regression tree method is extended to correlated survival data and applied to the problem of developing objective prognostic classification rules in periodontal research. The robust logrank statistic is used as the splitting statistic to measure the between-node difference in survival, while adjusting for correlation among failure times from the same patient. The partition-based survival function estimator is shown to converge to the true conditional survival function. Tooth loss data from 100 periodontal patients (2,509 teeth) was analyzed using the proposed method. The goal is to assign each tooth to one of the five prognosis categories (good, fair, poor, questionable, or hopeless). After the best-sized tree was identified, an amalgamation procedure was used to form five prognostic groups. The prognostic rules established here may be used by periodontists, general dentists, and insurance companies in devising appropriate treatment plans for periodontal oatients.
UR - http://www.scopus.com/inward/record.url?scp=33748861409&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33748861409&partnerID=8YFLogxK
U2 - 10.1198/016214506000000438
DO - 10.1198/016214506000000438
M3 - Review article
AN - SCOPUS:33748861409
VL - 101
SP - 959
EP - 967
JO - Journal of the American Statistical Association
JF - Journal of the American Statistical Association
SN - 0162-1459
IS - 475
ER -