TY - JOUR
T1 - Trends and Outcomes of Hospitalizations Related to Acute Pancreatitis
T2 - Epidemiology from 2001 to 2014 in the United States
AU - Gapp, Jonathan
AU - Hall, Alexander G.
AU - Walters, Ryan W.
AU - Jahann, Darius
AU - Kassim, Thamer
AU - Reddymasu, Savio
N1 - Funding Information:
Hospitalization data were abstracted from the NIS from 2001 to 2014. The NIS is part of a family of databases within the Healthcare Cost and Utilization Project sponsored by the Agency for Healthcare Research and Quality. The NIS is the largest publicly available, all-payer inpatient database in the United States and uses stratified random sampling that, when weighted, estimates approximately 35 million yearly hospitalizations nationally.5 The study period from 2001 to 2014 was selected specifically to maintain consistent International Classification of Disease, Ninth Revision, Clinical Modification (ICD-9-CM)/Procedure Coding System coding. Although the ICD-9-CM crosswalk to ICD-10-CM is straightforward for AP etiologies, this is not true for procedural coding, which precluded direct comparison before and after the October 2015 implementation of ICD-10-CM/Procedure Coding System. Therefore, to prevent confusion that could result from using different end dates when discussing AP etiologies versus procedures, we chose to present only results through 2014. However, we have included the 2015 and 2016 NIS data in Supplementary Tables 1 and 2 and Supplementary Figures 1 to 4, (http://links.lww.com/ MPA/A714) for every result specific to AP etiology.
PY - 2019/4/1
Y1 - 2019/4/1
N2 - Objectives The aim of this study was to determine the recent trends of the rates of hospitalization, mortality of hospitalized patients, and associated health care utilization in patients with acute pancreatitis (AP). Methods We identified adult patients with primary discharge diagnosis of AP from the National Inpatient Sample database. Patients with chronic pancreatitis and/or pancreatic cancer were excluded. Primary outcomes included age-adjusted incidence of AP and in-hospital mortality based on US standard population derived from the 2000 census data. Secondary outcomes were length of stay, inflation-adjusted hospital costs in 2014 US dollars, and procedural rates. Subgroup analysis included disease etiologies, age, race, sex, hospital region, hospital size, and institution type. Results From 2001 to 2014, the rate of primary discharge diagnosis for AP increased from 65.38 to 81.88 per 100,000 US adults per year. In-hospital case fatality decreased from 1.68% to 0.69%. Mortality rate is higher in patients with AP who are older than 65 years (3.4%). Length of stay decreased, with a median of 3.8 days; cost per hospitalization decreased since 2007 from $7602 to $6766 in 2014. Conclusions The rate of hospitalization related to AP in the United States continues to increase. Mortality, length of stay, and cost per hospitalization decrease. The increase in volume of hospitalization might contribute to an overall increase in health care resource utilization.
AB - Objectives The aim of this study was to determine the recent trends of the rates of hospitalization, mortality of hospitalized patients, and associated health care utilization in patients with acute pancreatitis (AP). Methods We identified adult patients with primary discharge diagnosis of AP from the National Inpatient Sample database. Patients with chronic pancreatitis and/or pancreatic cancer were excluded. Primary outcomes included age-adjusted incidence of AP and in-hospital mortality based on US standard population derived from the 2000 census data. Secondary outcomes were length of stay, inflation-adjusted hospital costs in 2014 US dollars, and procedural rates. Subgroup analysis included disease etiologies, age, race, sex, hospital region, hospital size, and institution type. Results From 2001 to 2014, the rate of primary discharge diagnosis for AP increased from 65.38 to 81.88 per 100,000 US adults per year. In-hospital case fatality decreased from 1.68% to 0.69%. Mortality rate is higher in patients with AP who are older than 65 years (3.4%). Length of stay decreased, with a median of 3.8 days; cost per hospitalization decreased since 2007 from $7602 to $6766 in 2014. Conclusions The rate of hospitalization related to AP in the United States continues to increase. Mortality, length of stay, and cost per hospitalization decrease. The increase in volume of hospitalization might contribute to an overall increase in health care resource utilization.
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U2 - 10.1097/MPA.0000000000001275
DO - 10.1097/MPA.0000000000001275
M3 - Article
C2 - 30946239
AN - SCOPUS:85064199862
VL - 48
SP - 548
EP - 554
JO - Pancreas
JF - Pancreas
SN - 0885-3177
IS - 4
ER -