Twelve-year survival after multiple recurrences and repeated metastasectomies for renal cell Carcinoma

Jue Wang, Geoffrey A. Talmon, Michael Feloney, Michael C. Morris

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Metastatic renal cell carcinoma (RCC) presents a therapeutic challenge for clinicians because of the unpredictable clinical course, resistance to chemotherapy or radiotherapy and the limited response to immunotherapy.Patients and Methods: We report a case of a 62-year-old woman who underwent nephrectomy for T4N0 RCC, clear cell type, Fuhrman grade 3/4 in 1999. The patinet subsequently had multiple tumor recurrences.Results: The patient underwent eight metastasectomies, including multiple partial left nephrectomies, right adrenalectomy, a complete left nephrectomy, and distal pancreatectomy. She remains well and tumor free 12 years after initial diagnosis.Conclusion: Repeated resections after initial metastasectomy can be carried out safely and provide long-term survival in selected patients with recurrent metastasis from RCC. The findings from our case indicate that close follow-up for the early detection of recurrence and complete resection of metastases can improve the results after repeated resection.

Original languageEnglish
Article number155
JournalWorld Journal of Surgical Oncology
Volume9
DOIs
StatePublished - Nov 28 2011
Externally publishedYes

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Metastasectomy
Nephrectomy
Renal Cell Carcinoma
Recurrence
Survival
Neoplasm Metastasis
Pancreatectomy
Adrenalectomy
Immunotherapy
Neoplasms
Radiotherapy
Drug Therapy
Therapeutics

All Science Journal Classification (ASJC) codes

  • Oncology
  • Surgery

Cite this

Twelve-year survival after multiple recurrences and repeated metastasectomies for renal cell Carcinoma. / Wang, Jue; Talmon, Geoffrey A.; Feloney, Michael; Morris, Michael C.

In: World Journal of Surgical Oncology, Vol. 9, 155, 28.11.2011.

Research output: Contribution to journalArticle

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