Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile: A potential pitfall for identification of USA300 community-associated MRSA

Anders Rhod Larsen; Richard Goering; Marc Stegger; Jodi A. Lindsay; Katherine A. Gould; Jason Hinds; Marit Sørum; Henrik Westh; Kit Boye; Robert Skov

doi:10.1128/JCM.00934-09

Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile: A potential pitfall for identification of USA300 community-associated MRSA

Anders Rhod Larsen, Richard Goering, Marc Stegger, Jodi A. Lindsay, Katherine A. Gould, Jason Hinds, Marit Sørum, Henrik Westh, Kit Boye, Robert Skov

Department of Medical Microbiology and Immunology

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Analysis of methicillin-resistant Staphylococcus aureus (MRSA) characterized as USA300 by pulsed-field gel electrophoresis identified two distinct clones. One was similar to community-associated USA300 MRSA (ST8-IVa, t008, and Panton-Valentine leukocidin positive). The second (ST8-IVa, t024, and PVL negative) had different molecular characteristics and epidemiology, suggesting independent evolution. We recommend spa typing and/or PCR to discriminate between the two clones.

Original language	English (US)
Pages (from-to)	3765-3768
Number of pages	4
Journal	Journal of clinical microbiology
Volume	47
Issue number	11
DOIs	https://doi.org/10.1128/JCM.00934-09
State	Published - Nov 2009

All Science Journal Classification (ASJC) codes

Microbiology (medical)

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10.1128/JCM.00934-09

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Larsen, A. R., Goering, R., Stegger, M., Lindsay, J. A., Gould, K. A., Hinds, J., Sørum, M., Westh, H., Boye, K., & Skov, R. (2009). Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile: A potential pitfall for identification of USA300 community-associated MRSA. Journal of clinical microbiology, 47(11), 3765-3768. https://doi.org/10.1128/JCM.00934-09

Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile : A potential pitfall for identification of USA300 community-associated MRSA. / Larsen, Anders Rhod; Goering, Richard; Stegger, Marc; Lindsay, Jodi A.; Gould, Katherine A.; Hinds, Jason; Sørum, Marit; Westh, Henrik; Boye, Kit; Skov, Robert.

In: Journal of clinical microbiology, Vol. 47, No. 11, 11.2009, p. 3765-3768.

Research output: Contribution to journal › Article › peer-review

Larsen, AR, Goering, R, Stegger, M, Lindsay, JA, Gould, KA, Hinds, J, Sørum, M, Westh, H, Boye, K & Skov, R 2009, 'Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile: A potential pitfall for identification of USA300 community-associated MRSA', Journal of clinical microbiology, vol. 47, no. 11, pp. 3765-3768. https://doi.org/10.1128/JCM.00934-09

Larsen AR, Goering R, Stegger M, Lindsay JA, Gould KA, Hinds J et al. Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile: A potential pitfall for identification of USA300 community-associated MRSA. Journal of clinical microbiology. 2009 Nov;47(11):3765-3768. https://doi.org/10.1128/JCM.00934-09

Larsen, Anders Rhod ; Goering, Richard ; Stegger, Marc ; Lindsay, Jodi A. ; Gould, Katherine A. ; Hinds, Jason ; Sørum, Marit ; Westh, Henrik ; Boye, Kit ; Skov, Robert. / Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile : A potential pitfall for identification of USA300 community-associated MRSA. In: Journal of clinical microbiology. 2009 ; Vol. 47, No. 11. pp. 3765-3768.

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abstract = "Analysis of methicillin-resistant Staphylococcus aureus (MRSA) characterized as USA300 by pulsed-field gel electrophoresis identified two distinct clones. One was similar to community-associated USA300 MRSA (ST8-IVa, t008, and Panton-Valentine leukocidin positive). The second (ST8-IVa, t024, and PVL negative) had different molecular characteristics and epidemiology, suggesting independent evolution. We recommend spa typing and/or PCR to discriminate between the two clones.",

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