Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile: A potential pitfall for identification of USA300 community-associated MRSA

Anders Rhod Larsen, Richard Goering, Marc Stegger, Jodi A. Lindsay, Katherine A. Gould, Jason Hinds, Marit Sørum, Henrik Westh, Kit Boye, Robert Skov

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Analysis of methicillin-resistant Staphylococcus aureus (MRSA) characterized as USA300 by pulsed-field gel electrophoresis identified two distinct clones. One was similar to community-associated USA300 MRSA (ST8-IVa, t008, and Panton-Valentine leukocidin positive). The second (ST8-IVa, t024, and PVL negative) had different molecular characteristics and epidemiology, suggesting independent evolution. We recommend spa typing and/or PCR to discriminate between the two clones.

Original languageEnglish (US)
Pages (from-to)3765-3768
Number of pages4
JournalJournal of clinical microbiology
Volume47
Issue number11
DOIs
StatePublished - Nov 1 2009

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

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