Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile: A potential pitfall for identification of USA300 community-associated MRSA

Anders Rhod Larsen, Richard V. Goering, Marc Stegger, Jodi A. Lindsay, Katherine A. Gould, Jason Hinds, Marit Sørum, Henrik Westh, Kit Boye, Robert Skov

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Analysis of methicillin-resistant Staphylococcus aureus (MRSA) characterized as USA300 by pulsed-field gel electrophoresis identified two distinct clones. One was similar to community-associated USA300 MRSA (ST8-IVa, t008, and Panton-Valentine leukocidin positive). The second (ST8-IVa, t024, and PVL negative) had different molecular characteristics and epidemiology, suggesting independent evolution. We recommend spa typing and/or PCR to discriminate between the two clones.

Original languageEnglish
Pages (from-to)3765-3768
Number of pages4
JournalJournal of Clinical Microbiology
Volume47
Issue number11
DOIs
StatePublished - Nov 2009

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Pulsed Field Gel Electrophoresis
Methicillin-Resistant Staphylococcus aureus
Clone Cells
Molecular Epidemiology
Polymerase Chain Reaction
Panton-Valentine leukocidin

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

Cite this

Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile : A potential pitfall for identification of USA300 community-associated MRSA. / Larsen, Anders Rhod; Goering, Richard V.; Stegger, Marc; Lindsay, Jodi A.; Gould, Katherine A.; Hinds, Jason; Sørum, Marit; Westh, Henrik; Boye, Kit; Skov, Robert.

In: Journal of Clinical Microbiology, Vol. 47, No. 11, 11.2009, p. 3765-3768.

Research output: Contribution to journalArticle

Larsen, Anders Rhod ; Goering, Richard V. ; Stegger, Marc ; Lindsay, Jodi A. ; Gould, Katherine A. ; Hinds, Jason ; Sørum, Marit ; Westh, Henrik ; Boye, Kit ; Skov, Robert. / Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile : A potential pitfall for identification of USA300 community-associated MRSA. In: Journal of Clinical Microbiology. 2009 ; Vol. 47, No. 11. pp. 3765-3768.
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