Two novel class I integron arrays containing IMP-18 metallo-β- lactamase gene in Pseudomonas aeruginosa clinical isolates from Puerto Rico

T. Martínez, G. J. Vazquez, E. E. Aquino, Richard V. Goering, I. E. Robledo

Research output: Contribution to journalArticle

14 Scopus citations


During a β-lactam resistance surveillance study, 12 IMP-18-positive Pseudomonas aeruginosa isolates belonging to 9 different pulsed-field gel electrophoresis groups were identified. In nine isolates, a class I integron with a novel gene array was identified that contained bla IMP-18 and bla OXA-224, while in two isolates the class I integron contained bla IMP-18 and bla OXA-2 but in a new arrangement. Our findings show the dissemination of two novel class I integrons in P. aeruginosa from different regions of Puerto Rico.

Original languageEnglish
Pages (from-to)2119-2121
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Issue number4
Publication statusPublished - Apr 2012


All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)
  • Pharmacology
  • Infectious Diseases

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