Two novel class I integron arrays containing IMP-18 metallo-β- lactamase gene in Pseudomonas aeruginosa clinical isolates from Puerto Rico

T. Martínez, G. J. Vazquez, E. E. Aquino, Richard V. Goering, I. E. Robledo

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

During a β-lactam resistance surveillance study, 12 IMP-18-positive Pseudomonas aeruginosa isolates belonging to 9 different pulsed-field gel electrophoresis groups were identified. In nine isolates, a class I integron with a novel gene array was identified that contained bla IMP-18 and bla OXA-224, while in two isolates the class I integron contained bla IMP-18 and bla OXA-2 but in a new arrangement. Our findings show the dissemination of two novel class I integrons in P. aeruginosa from different regions of Puerto Rico.

Original languageEnglish
Pages (from-to)2119-2121
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume56
Issue number4
DOIs
StatePublished - Apr 2012

Fingerprint

Integrons
Puerto Rico
Inosine Monophosphate
Pseudomonas aeruginosa
Genes
Lactams
Pulsed Field Gel Electrophoresis
Asp(5)-oxytocin

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)
  • Pharmacology
  • Infectious Diseases

Cite this

Two novel class I integron arrays containing IMP-18 metallo-β- lactamase gene in Pseudomonas aeruginosa clinical isolates from Puerto Rico. / Martínez, T.; Vazquez, G. J.; Aquino, E. E.; Goering, Richard V.; Robledo, I. E.

In: Antimicrobial Agents and Chemotherapy, Vol. 56, No. 4, 04.2012, p. 2119-2121.

Research output: Contribution to journalArticle

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