Update on Blood Pressure Control and Renal Outcomes in Diabetes Mellitus

Mark Henry Joven, Robert J. Anderson

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

Diabetic nephropathy (DN) is associated with a high incidence of cardiovascular (CV) morbidity and mortality. Although relationships between hypertension and diabetic nephropathy are complex, blood pressure (BP) control is an important management strategy in the prevention of onset and progression of DN in patients with diabetes mellitus (DM). Recent guidelines recommend less stringent BP targets among patients with type 2 DM and chronic kidney disease. These recommendations are based mostly on lack of benefit in CV outcomes with a low BP target. We review the current information on efficacy of BP control in improving renal outcomes in patients with type 2 DM. Presently, although intensive BP control has been was beneficial in decreasing albuminuria, it has not translated into reductions in risks of hard renal endpoints, such as progression to end-stage renal disease, the need for renal replacement therapy, and mortality from renal causes.

Original languageEnglish
Article number44
JournalCurrent Diabetes Reports
Volume15
Issue number7
DOIs
StatePublished - Jul 26 2015

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Diabetes Mellitus
Diabetic Nephropathies
Blood Pressure
Kidney
Type 2 Diabetes Mellitus
Albuminuria
Renal Replacement Therapy
Mortality
Risk Reduction Behavior
Chronic Renal Insufficiency
Hypotension
Chronic Kidney Failure
Guidelines
Hypertension
Morbidity
Incidence

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

Update on Blood Pressure Control and Renal Outcomes in Diabetes Mellitus. / Joven, Mark Henry; Anderson, Robert J.

In: Current Diabetes Reports, Vol. 15, No. 7, 44, 26.07.2015.

Research output: Contribution to journalReview article

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