Update on familial pancreatic cancer

Henry T. Lynch, Randall E. Brand, Carolyn A. Deters, Ramon M. Fusaro

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Approximately 5% to 10% of patients with pancreatic cancer have one or more first-degree relatives with this disease. A subset of these individuals have a hereditary form of pancreatic cancer designated by association with such hereditary disorders as familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, hereditary pancreatitis, or familial atypical multiple mole melanoma (FAMMM) syndrome. A subset of those FAMMM kindred with the CDKN2A (p16) germline mutation that expresses both pancreatic cancer and malignant melanoma may constitute a new hereditary pancreatic cancer-prone syndrome.

Original languageEnglish (US)
Pages (from-to)121-128
Number of pages8
JournalCurrent gastroenterology reports
Issue number2
StatePublished - Apr 2001

All Science Journal Classification (ASJC) codes

  • Gastroenterology


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