Update on familial pancreatic cancer

Henry T. Lynch; Randall E. Brand; Carolyn A. Deters; Ramon M. Fusaro

doi:10.1007/s11894-001-0008-5

Update on familial pancreatic cancer

Henry T. Lynch, Randall E. Brand, Carolyn A. Deters, Ramon M. Fusaro

Department of Preventive Medicine

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

Approximately 5% to 10% of patients with pancreatic cancer have one or more first-degree relatives with this disease. A subset of these individuals have a hereditary form of pancreatic cancer designated by association with such hereditary disorders as familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, hereditary pancreatitis, or familial atypical multiple mole melanoma (FAMMM) syndrome. A subset of those FAMMM kindred with the CDKN2A (p16) germline mutation that expresses both pancreatic cancer and malignant melanoma may constitute a new hereditary pancreatic cancer-prone syndrome.

Original language	English (US)
Pages (from-to)	121-128
Number of pages	8
Journal	Current gastroenterology reports
Volume	3
Issue number	2
DOIs	https://doi.org/10.1007/s11894-001-0008-5
State	Published - Apr 2001

All Science Journal Classification (ASJC) codes

Gastroenterology

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10.1007/s11894-001-0008-5

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title = "Update on familial pancreatic cancer",

abstract = "Approximately 5% to 10% of patients with pancreatic cancer have one or more first-degree relatives with this disease. A subset of these individuals have a hereditary form of pancreatic cancer designated by association with such hereditary disorders as familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, hereditary pancreatitis, or familial atypical multiple mole melanoma (FAMMM) syndrome. A subset of those FAMMM kindred with the CDKN2A (p16) germline mutation that expresses both pancreatic cancer and malignant melanoma may constitute a new hereditary pancreatic cancer-prone syndrome.",

author = "Lynch, {Henry T.} and Brand, {Randall E.} and Deters, {Carolyn A.} and Fusaro, {Ramon M.}",

year = "2001",

month = apr,

doi = "10.1007/s11894-001-0008-5",

language = "English (US)",

volume = "3",

pages = "121--128",

journal = "Current Gastroenterology Reports",

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T1 - Update on familial pancreatic cancer

AU - Lynch, Henry T.

AU - Brand, Randall E.

AU - Deters, Carolyn A.

AU - Fusaro, Ramon M.

PY - 2001/4

Y1 - 2001/4

N2 - Approximately 5% to 10% of patients with pancreatic cancer have one or more first-degree relatives with this disease. A subset of these individuals have a hereditary form of pancreatic cancer designated by association with such hereditary disorders as familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, hereditary pancreatitis, or familial atypical multiple mole melanoma (FAMMM) syndrome. A subset of those FAMMM kindred with the CDKN2A (p16) germline mutation that expresses both pancreatic cancer and malignant melanoma may constitute a new hereditary pancreatic cancer-prone syndrome.

AB - Approximately 5% to 10% of patients with pancreatic cancer have one or more first-degree relatives with this disease. A subset of these individuals have a hereditary form of pancreatic cancer designated by association with such hereditary disorders as familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, hereditary pancreatitis, or familial atypical multiple mole melanoma (FAMMM) syndrome. A subset of those FAMMM kindred with the CDKN2A (p16) germline mutation that expresses both pancreatic cancer and malignant melanoma may constitute a new hereditary pancreatic cancer-prone syndrome.

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U2 - 10.1007/s11894-001-0008-5

DO - 10.1007/s11894-001-0008-5

M3 - Review article

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SP - 121

EP - 128

JO - Current Gastroenterology Reports

JF - Current Gastroenterology Reports

SN - 1522-8037

IS - 2

ER -

Update on familial pancreatic cancer

Abstract

All Science Journal Classification (ASJC) codes

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