Update on familial pancreatic cancer

Henry T. Lynch, Randall E. Brand, Carolyn A. Deters, Ramon M. Fusaro

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

Approximately 5% to 10% of patients with pancreatic cancer have one or more first-degree relatives with this disease. A subset of these individuals have a hereditary form of pancreatic cancer designated by association with such hereditary disorders as familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, hereditary pancreatitis, or familial atypical multiple mole melanoma (FAMMM) syndrome. A subset of those FAMMM kindred with the CDKN2A (p16) germline mutation that expresses both pancreatic cancer and malignant melanoma may constitute a new hereditary pancreatic cancer-prone syndrome.

Original languageEnglish (US)
Pages (from-to)121-128
Number of pages8
JournalCurrent gastroenterology reports
Volume3
Issue number2
DOIs
StatePublished - Apr 2001

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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    Lynch, H. T., Brand, R. E., Deters, C. A., & Fusaro, R. M. (2001). Update on familial pancreatic cancer. Current gastroenterology reports, 3(2), 121-128. https://doi.org/10.1007/s11894-001-0008-5