Update on familial pancreatic cancer.

Henry T. Lynch, R. E. Brand, C. A. Deters, R. M. Fusaro

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Approximately 5% to 10% of patients with pancreatic cancer have one or more first-degree relatives with this disease. A subset of these individuals have a hereditary form of pancreatic cancer designated by association with such hereditary disorders as familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, hereditary pancreatitis, or familial atypical multiple mole melanoma (FAMMM) syndrome. A subset of those FAMMM kindred with the CDKN2A (p16) germline mutation that expresses both pancreatic cancer and malignant melanoma may constitute a new hereditary pancreatic cancer-prone syndrome.

Original languageEnglish
Pages (from-to)121-128
Number of pages8
JournalCurrent Gastroenterology Reports
Volume3
Issue number2
StatePublished - Apr 2001

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Pancreatic Neoplasms
Dysplastic Nevus Syndrome
Hereditary Nonpolyposis Colorectal Neoplasms
Adenomatous Polyposis Coli
Germ-Line Mutation
Melanoma

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Lynch, H. T., Brand, R. E., Deters, C. A., & Fusaro, R. M. (2001). Update on familial pancreatic cancer. Current Gastroenterology Reports, 3(2), 121-128.

Update on familial pancreatic cancer. / Lynch, Henry T.; Brand, R. E.; Deters, C. A.; Fusaro, R. M.

In: Current Gastroenterology Reports, Vol. 3, No. 2, 04.2001, p. 121-128.

Research output: Contribution to journalReview article

Lynch, HT, Brand, RE, Deters, CA & Fusaro, RM 2001, 'Update on familial pancreatic cancer.', Current Gastroenterology Reports, vol. 3, no. 2, pp. 121-128.
Lynch HT, Brand RE, Deters CA, Fusaro RM. Update on familial pancreatic cancer. Current Gastroenterology Reports. 2001 Apr;3(2):121-128.
Lynch, Henry T. ; Brand, R. E. ; Deters, C. A. ; Fusaro, R. M. / Update on familial pancreatic cancer. In: Current Gastroenterology Reports. 2001 ; Vol. 3, No. 2. pp. 121-128.
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