Abstract
Approximately 5% to 10% of patients with pancreatic cancer have one or more first-degree relatives with this disease. A subset of these individuals have a hereditary form of pancreatic cancer designated by association with such hereditary disorders as familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, hereditary pancreatitis, or familial atypical multiple mole melanoma (FAMMM) syndrome. A subset of those FAMMM kindred with the CDKN2A (p16) germline mutation that expresses both pancreatic cancer and malignant melanoma may constitute a new hereditary pancreatic cancer-prone syndrome.
| Original language | English |
|---|---|
| Pages (from-to) | 121-128 |
| Number of pages | 8 |
| Journal | Current Gastroenterology Reports |
| Volume | 3 |
| Issue number | 2 |
| State | Published - Apr 2001 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
Cite this
Update on familial pancreatic cancer. / Lynch, Henry T.; Brand, R. E.; Deters, C. A.; Fusaro, R. M.
In: Current Gastroenterology Reports, Vol. 3, No. 2, 04.2001, p. 121-128.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Update on familial pancreatic cancer.
AU - Lynch, Henry T.
AU - Brand, R. E.
AU - Deters, C. A.
AU - Fusaro, R. M.
PY - 2001/4
Y1 - 2001/4
N2 - Approximately 5% to 10% of patients with pancreatic cancer have one or more first-degree relatives with this disease. A subset of these individuals have a hereditary form of pancreatic cancer designated by association with such hereditary disorders as familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, hereditary pancreatitis, or familial atypical multiple mole melanoma (FAMMM) syndrome. A subset of those FAMMM kindred with the CDKN2A (p16) germline mutation that expresses both pancreatic cancer and malignant melanoma may constitute a new hereditary pancreatic cancer-prone syndrome.
AB - Approximately 5% to 10% of patients with pancreatic cancer have one or more first-degree relatives with this disease. A subset of these individuals have a hereditary form of pancreatic cancer designated by association with such hereditary disorders as familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, hereditary pancreatitis, or familial atypical multiple mole melanoma (FAMMM) syndrome. A subset of those FAMMM kindred with the CDKN2A (p16) germline mutation that expresses both pancreatic cancer and malignant melanoma may constitute a new hereditary pancreatic cancer-prone syndrome.
UR - http://www.scopus.com/inward/record.url?scp=0001762524&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0001762524&partnerID=8YFLogxK
M3 - Review article
VL - 3
SP - 121
EP - 128
JO - Current Gastroenterology Reports
JF - Current Gastroenterology Reports
SN - 1522-8037
IS - 2
ER -