Abstract
Approximately 5% to 10% of patients with pancreatic cancer have one or more first-degree relatives with this disease. A subset of these individuals have a hereditary form of pancreatic cancer designated by association with such hereditary disorders as familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, hereditary pancreatitis, or familial atypical multiple mole melanoma (FAMMM) syndrome. A subset of those FAMMM kindred with the CDKN2A (p16) germline mutation that expresses both pancreatic cancer and malignant melanoma may constitute a new hereditary pancreatic cancer-prone syndrome.
Original language | English (US) |
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Pages (from-to) | 121-128 |
Number of pages | 8 |
Journal | Current gastroenterology reports |
Volume | 3 |
Issue number | 2 |
DOIs | |
State | Published - Apr 2001 |
All Science Journal Classification (ASJC) codes
- Gastroenterology