Abstract
The cochlea outer hair cell (OHC) is a sensory receptor cell that exerts a force when electrically stimulated. In order to analyze the mechanical properties of OHC and its force generation, a mathematical model was used based on a neural modeling program Genesis. The model was implemented as a thin-shell fluid-filled closed cylinder whose passive membrane properties were described by two elastic parameters: area modulus and shear modulus. The axial compliance of the model cells increases linearly with length. The force generated against a constant load increases with the cell length. The isometric force is independent of cell length but dependent of the two elastic parameters.
| Original language | English |
|---|---|
| Title of host publication | Southern Biomedical Engineering Conference - Proceedings |
| Publisher | IEEE |
| Pages | 88 |
| Number of pages | 1 |
| State | Published - 1998 |
| Externally published | Yes |
| Event | Proceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA Duration: Feb 6 1998 → Feb 8 1998 |
Other
| Other | Proceedings of the 1998 17th Southern Biomedical Engineering Conference |
|---|---|
| City | San Antonio, TX, USA |
| Period | 2/6/98 → 2/8/98 |
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All Science Journal Classification (ASJC) codes
- Engineering(all)
Cite this
Use of neural modeling programs in simulating tissue mechanics and active force generation. / Hallworth, Richard J.; Nowakowski, Ryan; Gureckis, Todd.
Southern Biomedical Engineering Conference - Proceedings. IEEE, 1998. p. 88.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Use of neural modeling programs in simulating tissue mechanics and active force generation
AU - Hallworth, Richard J.
AU - Nowakowski, Ryan
AU - Gureckis, Todd
PY - 1998
Y1 - 1998
N2 - The cochlea outer hair cell (OHC) is a sensory receptor cell that exerts a force when electrically stimulated. In order to analyze the mechanical properties of OHC and its force generation, a mathematical model was used based on a neural modeling program Genesis. The model was implemented as a thin-shell fluid-filled closed cylinder whose passive membrane properties were described by two elastic parameters: area modulus and shear modulus. The axial compliance of the model cells increases linearly with length. The force generated against a constant load increases with the cell length. The isometric force is independent of cell length but dependent of the two elastic parameters.
AB - The cochlea outer hair cell (OHC) is a sensory receptor cell that exerts a force when electrically stimulated. In order to analyze the mechanical properties of OHC and its force generation, a mathematical model was used based on a neural modeling program Genesis. The model was implemented as a thin-shell fluid-filled closed cylinder whose passive membrane properties were described by two elastic parameters: area modulus and shear modulus. The axial compliance of the model cells increases linearly with length. The force generated against a constant load increases with the cell length. The isometric force is independent of cell length but dependent of the two elastic parameters.
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UR - http://www.scopus.com/inward/citedby.url?scp=0031653946&partnerID=8YFLogxK
M3 - Conference contribution
SP - 88
BT - Southern Biomedical Engineering Conference - Proceedings
PB - IEEE
ER -