### Abstract

The cochlea outer hair cell (OHC) is a sensory receptor cell that exerts a force when electrically stimulated. In order to analyze the mechanical properties of OHC and its force generation, a mathematical model was used based on a neural modeling program Genesis. The model was implemented as a thin-shell fluid-filled closed cylinder whose passive membrane properties were described by two elastic parameters: area modulus and shear modulus. The axial compliance of the model cells increases linearly with length. The force generated against a constant load increases with the cell length. The isometric force is independent of cell length but dependent of the two elastic parameters.

Original language | English |
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Title of host publication | Southern Biomedical Engineering Conference - Proceedings |

Publisher | IEEE |

Pages | 88 |

Number of pages | 1 |

State | Published - 1998 |

Externally published | Yes |

Event | Proceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA Duration: Feb 6 1998 → Feb 8 1998 |

### Other

Other | Proceedings of the 1998 17th Southern Biomedical Engineering Conference |
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City | San Antonio, TX, USA |

Period | 2/6/98 → 2/8/98 |

### Fingerprint

### All Science Journal Classification (ASJC) codes

- Engineering(all)

### Cite this

*Southern Biomedical Engineering Conference - Proceedings*(pp. 88). IEEE.

**Use of neural modeling programs in simulating tissue mechanics and active force generation.** / Hallworth, Richard J.; Nowakowski, Ryan; Gureckis, Todd.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

*Southern Biomedical Engineering Conference - Proceedings.*IEEE, pp. 88, Proceedings of the 1998 17th Southern Biomedical Engineering Conference, San Antonio, TX, USA, 2/6/98.

}

TY - GEN

T1 - Use of neural modeling programs in simulating tissue mechanics and active force generation

AU - Hallworth, Richard J.

AU - Nowakowski, Ryan

AU - Gureckis, Todd

PY - 1998

Y1 - 1998

N2 - The cochlea outer hair cell (OHC) is a sensory receptor cell that exerts a force when electrically stimulated. In order to analyze the mechanical properties of OHC and its force generation, a mathematical model was used based on a neural modeling program Genesis. The model was implemented as a thin-shell fluid-filled closed cylinder whose passive membrane properties were described by two elastic parameters: area modulus and shear modulus. The axial compliance of the model cells increases linearly with length. The force generated against a constant load increases with the cell length. The isometric force is independent of cell length but dependent of the two elastic parameters.

AB - The cochlea outer hair cell (OHC) is a sensory receptor cell that exerts a force when electrically stimulated. In order to analyze the mechanical properties of OHC and its force generation, a mathematical model was used based on a neural modeling program Genesis. The model was implemented as a thin-shell fluid-filled closed cylinder whose passive membrane properties were described by two elastic parameters: area modulus and shear modulus. The axial compliance of the model cells increases linearly with length. The force generated against a constant load increases with the cell length. The isometric force is independent of cell length but dependent of the two elastic parameters.

UR - http://www.scopus.com/inward/record.url?scp=0031653946&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031653946&partnerID=8YFLogxK

M3 - Conference contribution

SP - 88

BT - Southern Biomedical Engineering Conference - Proceedings

PB - IEEE

ER -