Abstract
The cochlea outer hair cell (OHC) is a sensory receptor cell that exerts a force when electrically stimulated. In order to analyze the mechanical properties of OHC and its force generation, a mathematical model was used based on a neural modeling program Genesis. The model was implemented as a thin-shell fluid-filled closed cylinder whose passive membrane properties were described by two elastic parameters: area modulus and shear modulus. The axial compliance of the model cells increases linearly with length. The force generated against a constant load increases with the cell length. The isometric force is independent of cell length but dependent of the two elastic parameters.
| Original language | English |
|---|---|
| Title of host publication | Southern Biomedical Engineering Conference - Proceedings |
| Publisher | IEEE |
| Pages | 88 |
| Number of pages | 1 |
| Publication status | Published - 1998 |
| Externally published | Yes |
| Event | Proceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA Duration: Feb 6 1998 → Feb 8 1998 |
Other
| Other | Proceedings of the 1998 17th Southern Biomedical Engineering Conference |
|---|---|
| City | San Antonio, TX, USA |
| Period | 2/6/98 → 2/8/98 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Engineering(all)
Cite this
Hallworth, R. J., Nowakowski, R., & Gureckis, T. (1998). Use of neural modeling programs in simulating tissue mechanics and active force generation. In Southern Biomedical Engineering Conference - Proceedings (pp. 88). IEEE.