Utility of antidiabetes medications in chronic kidney disease: A review

There is a large body of evidence describing the utility of antidiabetes agents in people with chronic kidney disease (CKD). Clinical decisions should take into account the pharmacokinetic variability and potential adverse events seen when these agents are used in renally impaired patients. In this article, the authors review the literature and summarise which antidiabetes agents are safe, with dose reductions if necessary, in people with CKD.