TY - JOUR
T1 - Video Capsule Endoscopy
T2 - What Is the Role in Surveillance of Hereditary Colon Cancer Syndromes?
AU - Lynch, Henry T.
AU - Burke, Carol A.
N1 - Funding Information:
This article was supported by revenue from Nebraska cigarette taxes awarded to Creighton University and to the University of Nebraska Medical Center by the Nebraska Department of Health and Human Services. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the State of Nebraska or the Nebraska Department of Health and Human Services. Support was also received from NIH Grant #1U01 CA86389, and through a grant awarded by the Jacqueline Seroussi Memorial Foundation.
PY - 2006/7
Y1 - 2006/7
N2 - Video capsule endoscopy (VCE) is a new technology which has proven to be effective for screening of the entire small bowel in those hereditary colon cancer-prone disorders that predispose to small bowel polyps and small bowel cancer (SBC). VCE appears to be superior to both barium studies and push enteroscopy for diagnosis of small bowel lesions in these disorders. However, in the interest of maximum benefit to our high-risk patients, the endoscopist must fully understand the natural history of hereditary colorectal cancer (CRC) disorders and their molecular genetics. It is in this realm that a comprehensive cancer family history will be of great benefit in allowing greater certainty in diagnosis and, in particular, in ability to focus on the specific germline mutation that may help to confirm the hereditary CRC syndrome of concern.
AB - Video capsule endoscopy (VCE) is a new technology which has proven to be effective for screening of the entire small bowel in those hereditary colon cancer-prone disorders that predispose to small bowel polyps and small bowel cancer (SBC). VCE appears to be superior to both barium studies and push enteroscopy for diagnosis of small bowel lesions in these disorders. However, in the interest of maximum benefit to our high-risk patients, the endoscopist must fully understand the natural history of hereditary colorectal cancer (CRC) disorders and their molecular genetics. It is in this realm that a comprehensive cancer family history will be of great benefit in allowing greater certainty in diagnosis and, in particular, in ability to focus on the specific germline mutation that may help to confirm the hereditary CRC syndrome of concern.
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U2 - 10.1016/j.tgie.2006.04.003
DO - 10.1016/j.tgie.2006.04.003
M3 - Article
AN - SCOPUS:33745937462
VL - 8
SP - 126
EP - 132
JO - Techniques in Gastrointestinal Endoscopy
JF - Techniques in Gastrointestinal Endoscopy
SN - 1096-2883
IS - 3
ER -