Vitamin D and calcium interactions: Functional outcomes

Robert P. Heaney

Research output: Contribution to journalReview article

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I present the results of published studies and original data and describe the functional outcomes of effects related to the interaction between vitamin D status and calcium intake. These effects fall into 3 broad categories: 1) synergistic effects of vitamin D status and calcium intake on calcium absorption; 2) effects of calcium intake on vitamin D status; and 3) largely observational data suggesting an association between calcium and vitamin D status and nonskeletal outcomes, such as cancer. To a considerable extent, both vitamin D status and the benefits associated therewith appear to be dependent on, or at least augmented by, calcium intakes at or above currently recommended levels.

Original languageEnglish
JournalAmerican Journal of Clinical Nutrition
Issue number2
Publication statusPublished - Aug 1 2008


All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Food Science
  • Nutrition and Dietetics

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