Vitamin D and calcium interactions: Functional outcomes

Robert P. Heaney

Research output: Contribution to journalReview articlepeer-review

118 Scopus citations


I present the results of published studies and original data and describe the functional outcomes of effects related to the interaction between vitamin D status and calcium intake. These effects fall into 3 broad categories: 1) synergistic effects of vitamin D status and calcium intake on calcium absorption; 2) effects of calcium intake on vitamin D status; and 3) largely observational data suggesting an association between calcium and vitamin D status and nonskeletal outcomes, such as cancer. To a considerable extent, both vitamin D status and the benefits associated therewith appear to be dependent on, or at least augmented by, calcium intakes at or above currently recommended levels.

Original languageEnglish (US)
Pages (from-to)541S-544S
JournalAmerican Journal of Clinical Nutrition
Issue number2
StatePublished - Aug 1 2008

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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