Abstract
On September 29, 2011, acknowledged experts in the field of vitamin D, mainly European, were brought together in order to discuss the recent scientific advances in relation to vitamin D: the current requirements and associations with various health outcomes. In this article, the discussions resulting from the meeting are summarized. Introduction: Several groups at risk for developing vitamin D insufficiency have been identified. Accordingly, reviews indicate that a significant percentage of the population worldwide have serum 25-hydroxyvitamin D levels below 50 nmol/l. In addition to the role of vitamin D in bone health, recent studies suggest that it may play a pivotal role in other systems, e.g., the cardiovascular system, pancreas, muscle, immune system and brain. Most evidence, however, is obtained from observational studies and yet inconclusive. Methods: To exchange and broaden knowledge on the requirements for vitamin D and its effect on various health outcomes, a workshop entitled "Vitamin D Expert Meeting: Do we get enough?", was organized. Results: Despite low vitamin D levels worldwide, consensus on the definition of deficiency is not yet reached. In order to define cut-off points for vitamin D whilst taking into account extraskeletal health effects, randomized controlled trials in these fields are warranted. The experts do emphasize that there is evidence to suggest an important role for vitamin D in the maintenance of optimal bone health at all ages and that vitamin D supplementation, in most studies co-administered with calcium, reduces fracture risk in the senior population. Conclusion: To reach a serum 25-hydroxyvitamin D level of 50 nmol/l older adults aged ≥65 years are therefore recommended to meet a mean daily vitamin D intake of 20 μg (800 IU), which is best achieved with a supplement.
| Original language | English |
|---|---|
| Pages (from-to) | 1567-1577 |
| Number of pages | 11 |
| Journal | Osteoporosis International |
| Volume | 24 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 2013 |
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All Science Journal Classification (ASJC) codes
- Endocrinology, Diabetes and Metabolism
Cite this
Vitamin D : Do we get enough?: A discussion between vitamin D experts in order to make a step towards the harmonisation of dietary reference intakes for vitamin D across Europe. / Brouwer-Brolsma, E. M.; Bischoff-Ferrari, H. A.; Bouillon, R.; Feskens, E. J M; Gallagher, John Christopher G.; Hypponen, E.; Llewellyn, D. J.; Stoecklin, E.; Dierkes, J.; Kies, A. K.; Kok, F. J.; Lamberg-Allardt, C.; Moser, U.; Pilz, S.; Saris, W. H.; Van Schoor, N. M.; Weber, P.; Witkamp, R.; Zittermann, A.; De Groot, L. C P G M.
In: Osteoporosis International, Vol. 24, No. 5, 05.2013, p. 1567-1577.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Vitamin D
T2 - Do we get enough?: A discussion between vitamin D experts in order to make a step towards the harmonisation of dietary reference intakes for vitamin D across Europe
AU - Brouwer-Brolsma, E. M.
AU - Bischoff-Ferrari, H. A.
AU - Bouillon, R.
AU - Feskens, E. J M
AU - Gallagher, John Christopher G.
AU - Hypponen, E.
AU - Llewellyn, D. J.
AU - Stoecklin, E.
AU - Dierkes, J.
AU - Kies, A. K.
AU - Kok, F. J.
AU - Lamberg-Allardt, C.
AU - Moser, U.
AU - Pilz, S.
AU - Saris, W. H.
AU - Van Schoor, N. M.
AU - Weber, P.
AU - Witkamp, R.
AU - Zittermann, A.
AU - De Groot, L. C P G M
PY - 2013/5
Y1 - 2013/5
N2 - On September 29, 2011, acknowledged experts in the field of vitamin D, mainly European, were brought together in order to discuss the recent scientific advances in relation to vitamin D: the current requirements and associations with various health outcomes. In this article, the discussions resulting from the meeting are summarized. Introduction: Several groups at risk for developing vitamin D insufficiency have been identified. Accordingly, reviews indicate that a significant percentage of the population worldwide have serum 25-hydroxyvitamin D levels below 50 nmol/l. In addition to the role of vitamin D in bone health, recent studies suggest that it may play a pivotal role in other systems, e.g., the cardiovascular system, pancreas, muscle, immune system and brain. Most evidence, however, is obtained from observational studies and yet inconclusive. Methods: To exchange and broaden knowledge on the requirements for vitamin D and its effect on various health outcomes, a workshop entitled "Vitamin D Expert Meeting: Do we get enough?", was organized. Results: Despite low vitamin D levels worldwide, consensus on the definition of deficiency is not yet reached. In order to define cut-off points for vitamin D whilst taking into account extraskeletal health effects, randomized controlled trials in these fields are warranted. The experts do emphasize that there is evidence to suggest an important role for vitamin D in the maintenance of optimal bone health at all ages and that vitamin D supplementation, in most studies co-administered with calcium, reduces fracture risk in the senior population. Conclusion: To reach a serum 25-hydroxyvitamin D level of 50 nmol/l older adults aged ≥65 years are therefore recommended to meet a mean daily vitamin D intake of 20 μg (800 IU), which is best achieved with a supplement.
AB - On September 29, 2011, acknowledged experts in the field of vitamin D, mainly European, were brought together in order to discuss the recent scientific advances in relation to vitamin D: the current requirements and associations with various health outcomes. In this article, the discussions resulting from the meeting are summarized. Introduction: Several groups at risk for developing vitamin D insufficiency have been identified. Accordingly, reviews indicate that a significant percentage of the population worldwide have serum 25-hydroxyvitamin D levels below 50 nmol/l. In addition to the role of vitamin D in bone health, recent studies suggest that it may play a pivotal role in other systems, e.g., the cardiovascular system, pancreas, muscle, immune system and brain. Most evidence, however, is obtained from observational studies and yet inconclusive. Methods: To exchange and broaden knowledge on the requirements for vitamin D and its effect on various health outcomes, a workshop entitled "Vitamin D Expert Meeting: Do we get enough?", was organized. Results: Despite low vitamin D levels worldwide, consensus on the definition of deficiency is not yet reached. In order to define cut-off points for vitamin D whilst taking into account extraskeletal health effects, randomized controlled trials in these fields are warranted. The experts do emphasize that there is evidence to suggest an important role for vitamin D in the maintenance of optimal bone health at all ages and that vitamin D supplementation, in most studies co-administered with calcium, reduces fracture risk in the senior population. Conclusion: To reach a serum 25-hydroxyvitamin D level of 50 nmol/l older adults aged ≥65 years are therefore recommended to meet a mean daily vitamin D intake of 20 μg (800 IU), which is best achieved with a supplement.
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UR - http://www.scopus.com/inward/citedby.url?scp=84885020653&partnerID=8YFLogxK
U2 - 10.1007/s00198-012-2231-3
DO - 10.1007/s00198-012-2231-3
M3 - Review article
VL - 24
SP - 1567
EP - 1577
JO - Osteoporosis International
JF - Osteoporosis International
SN - 0937-941X
IS - 5
ER -