Vitamin D endocrine physiology

Robert P. Heaney

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Quantitative aspects of vitamin D3 endocrine physiology are briefly reviewed, together with the supporting evidence. Net calcium absorption of at least 200 mg/d is required to offset typical obligatory losses and thereby to protect the skeleton. The ability of the body to regulate intestinal calcium absorption is optimal at serum 25-hydroxyvitamin D3 concentrations >80 nM. Vitamin D3 inputs from all sources required to sustain such a level amount to 3600-4200 IU/d. Daily oral intakes as high as 10,000 IU are safe.

Original languageEnglish
JournalJournal of Bone and Mineral Research
Volume22
Issue numberSUPPL. 2
DOIs
StatePublished - Dec 2007

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Cholecalciferol
Vitamin D
Calcium
Calcifediol
Intestinal Absorption
Skeleton
Serum

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Vitamin D endocrine physiology. / Heaney, Robert P.

In: Journal of Bone and Mineral Research, Vol. 22, No. SUPPL. 2, 12.2007.

Research output: Contribution to journalArticle

Heaney, Robert P. / Vitamin D endocrine physiology. In: Journal of Bone and Mineral Research. 2007 ; Vol. 22, No. SUPPL. 2.
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