Abstract
A recent meta-analysis of 16 publications suggests that bone mineral density (BMD) is not associated with vitamin D receptor (VDR) gene polymorphism (VDRGP), p > 0.05, at all sites analyzed when false positive studies are excluded [7]. Although more papers are being published, results are still conflicting. We re-addressed this issue with an approach using two methods involving fuzzy mathematics, [4]. Fifty-five publications on spinal BMD were analyzed as were 73 publications on hip BMD. In this paper, an analysis by belief functions seems to confirm the findings of [4]. This analysis suggests that spinal BMD is associated with VDRGP in females before or after menopause. This BMD - VDR association is also evident in studies in populations males and females combined.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of the 6th Joint Conference on Information Sciences, JCIS 2002 |
| Editors | J.H. Caulfield, S.H. Chen, H.D. Cheng, R. Duro, J.H. Caufield, S.H. Chen, H.D. Cheng, R. Duro, V. Honavar |
| Pages | 164-167 |
| Number of pages | 4 |
| Volume | 6 |
| State | Published - 2002 |
| Event | Proceedings of the 6th Joint Conference on Information Sciences, JCIS 2002 - Research Triange Park, NC, United States Duration: Mar 8 2002 → Mar 13 2002 |
Other
| Other | Proceedings of the 6th Joint Conference on Information Sciences, JCIS 2002 |
|---|---|
| Country | United States |
| City | Research Triange Park, NC |
| Period | 3/8/02 → 3/13/02 |
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All Science Journal Classification (ASJC) codes
- Computer Science(all)
Cite this
Vitamin D Receptor Gene Polymorphism's Effect on Bone Mineral Density : Analysis by Use of Belief Functions. / Cheng, Shih-Chuan; Goetzinger, Alyssa A.; Mordeson, John N.
Proceedings of the 6th Joint Conference on Information Sciences, JCIS 2002. ed. / J.H. Caulfield; S.H. Chen; H.D. Cheng; R. Duro; J.H. Caufield; S.H. Chen; H.D. Cheng; R. Duro; V. Honavar. Vol. 6 2002. p. 164-167.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Vitamin D Receptor Gene Polymorphism's Effect on Bone Mineral Density
T2 - Analysis by Use of Belief Functions
AU - Cheng, Shih-Chuan
AU - Goetzinger, Alyssa A.
AU - Mordeson, John N.
PY - 2002
Y1 - 2002
N2 - A recent meta-analysis of 16 publications suggests that bone mineral density (BMD) is not associated with vitamin D receptor (VDR) gene polymorphism (VDRGP), p > 0.05, at all sites analyzed when false positive studies are excluded [7]. Although more papers are being published, results are still conflicting. We re-addressed this issue with an approach using two methods involving fuzzy mathematics, [4]. Fifty-five publications on spinal BMD were analyzed as were 73 publications on hip BMD. In this paper, an analysis by belief functions seems to confirm the findings of [4]. This analysis suggests that spinal BMD is associated with VDRGP in females before or after menopause. This BMD - VDR association is also evident in studies in populations males and females combined.
AB - A recent meta-analysis of 16 publications suggests that bone mineral density (BMD) is not associated with vitamin D receptor (VDR) gene polymorphism (VDRGP), p > 0.05, at all sites analyzed when false positive studies are excluded [7]. Although more papers are being published, results are still conflicting. We re-addressed this issue with an approach using two methods involving fuzzy mathematics, [4]. Fifty-five publications on spinal BMD were analyzed as were 73 publications on hip BMD. In this paper, an analysis by belief functions seems to confirm the findings of [4]. This analysis suggests that spinal BMD is associated with VDRGP in females before or after menopause. This BMD - VDR association is also evident in studies in populations males and females combined.
UR - http://www.scopus.com/inward/record.url?scp=1642339625&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=1642339625&partnerID=8YFLogxK
M3 - Conference contribution
SN - 0970789017
VL - 6
SP - 164
EP - 167
BT - Proceedings of the 6th Joint Conference on Information Sciences, JCIS 2002
A2 - Caulfield, J.H.
A2 - Chen, S.H.
A2 - Cheng, H.D.
A2 - Duro, R.
A2 - Caufield, J.H.
A2 - Chen, S.H.
A2 - Cheng, H.D.
A2 - Duro, R.
A2 - Honavar, V.
ER -