Vitamin D

The Iceberg Nutrient

Laura A G Armas, Robert P. Heaney

Research output: Contribution to journalReview article

16 Citations (Scopus)

Abstract

The understanding of vitamin D's role in human health has recently expanded. It is now recognized as more than a hormone activated in the kidney only for calcium homeostasis. It is metabolized and used by virtually every cell in the body. Patients with chronic kidney disease have a deficit in their kidney production of 1,25(OH)2D and have classically been treated with calcitriol or its active analogues. Despite often having lower systemic levels of 1,25(OH)2D, patients with chronic kidney disease retain the capability of extra renal production of 1,25(OH)2D. This has far reaching implications for their health. This review examines clinical trials and observations in 3 areas that impact chronic kidney disease patients. Cancer, cardiovascular disease and infections are responsible for much of the morbidity and mortality in this patient population. We will discuss vitamin D's role in these disease states with a focus on the chronic kidney disease patient.

Original languageEnglish
Pages (from-to)134-139
Number of pages6
JournalJournal of Renal Nutrition
Volume21
Issue number2
DOIs
StatePublished - Mar 2011

Fingerprint

Ice Cover
Vitamin D
Chronic Renal Insufficiency
Food
Kidney
Vitamins
Cardiovascular Infections
Calcitriol
Health
Homeostasis
Cardiovascular Diseases
Clinical Trials
Hormones
Calcium
Morbidity
Mortality
Population
Neoplasms

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Nephrology

Cite this

Vitamin D : The Iceberg Nutrient. / Armas, Laura A G; Heaney, Robert P.

In: Journal of Renal Nutrition, Vol. 21, No. 2, 03.2011, p. 134-139.

Research output: Contribution to journalReview article

Armas, Laura A G ; Heaney, Robert P. / Vitamin D : The Iceberg Nutrient. In: Journal of Renal Nutrition. 2011 ; Vol. 21, No. 2. pp. 134-139.
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