Water-soluble, isolable gold clusters protected by tiopronin and coenzyme a monolayers

Allen C. Templeton, Shaowei Chen, Stephen Gross, Royce W. Murray

Research output: Contribution to journalArticle

375 Citations (Scopus)

Abstract

Isolable, water-soluble gold clusters protected by monolayers of tiopronin (tiopronin-MPCs) or coenzyme A (CoA-MPCs) were synthesized by a procedure of comparable simplicity to the Brust synthesis for alkanethiolate monolayer-protected gold clusters. High-resolution transmission electron microscopy shows that, like their alkanethiolate-MPC counterparts, the average core diameters of tiopronin-MPCs can be systematically controlled by varying the tiopronin:Au mole ratio employed in the reaction. The UV-vis spectra of tiopronin-MPCs exhibit pH and core size dependency of the surface plasmon band position and intensity, respectively. Thermogravimetric analysis of the tiopronin-MPCs gave average numbers of tiopronin ligands per cluster; for example, tiopronin-MPCs with an average core size of 1.8 nm (∼Au201) are protected with an average of 85 tiopronin ligands. 1H NMR reveals a size-dependent evolution of spectral features interpreted as reflecting differences in attachment sites (terrace, defects) and/or restriction in ligand mobility. Infrared spectroscopy reveals strong hydrogen bonding in the monolayer and provides evidence for intercluster association, and acid/base titrations produce pKA values similar to the free ligand in the presence of a charge-screening supporting electrolyte, but higher in its absence. The same analytical methods were also applied to CoA-MPCs.

Original languageEnglish
Pages (from-to)66-76
Number of pages11
JournalLangmuir
Volume15
Issue number1
StatePublished - Jan 5 1999
Externally publishedYes

Fingerprint

Tiopronin
coenzymes
Coenzymes
Gold
Monolayers
Ligands
gold
ligands
Water
water
Coenzyme A
High resolution transmission electron microscopy
Titration
titration
attachment
Thermogravimetric analysis
Infrared spectroscopy
constrictions
Hydrogen bonds
Screening

All Science Journal Classification (ASJC) codes

  • Colloid and Surface Chemistry
  • Physical and Theoretical Chemistry

Cite this

Templeton, A. C., Chen, S., Gross, S., & Murray, R. W. (1999). Water-soluble, isolable gold clusters protected by tiopronin and coenzyme a monolayers. Langmuir, 15(1), 66-76.

Water-soluble, isolable gold clusters protected by tiopronin and coenzyme a monolayers. / Templeton, Allen C.; Chen, Shaowei; Gross, Stephen; Murray, Royce W.

In: Langmuir, Vol. 15, No. 1, 05.01.1999, p. 66-76.

Research output: Contribution to journalArticle

Templeton, AC, Chen, S, Gross, S & Murray, RW 1999, 'Water-soluble, isolable gold clusters protected by tiopronin and coenzyme a monolayers', Langmuir, vol. 15, no. 1, pp. 66-76.
Templeton, Allen C. ; Chen, Shaowei ; Gross, Stephen ; Murray, Royce W. / Water-soluble, isolable gold clusters protected by tiopronin and coenzyme a monolayers. In: Langmuir. 1999 ; Vol. 15, No. 1. pp. 66-76.
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