TY - JOUR
T1 - Worsening of renal function and uncontrolled hypertension from intravitreal bevacizumab injections
AU - Ahmed, Moeed
AU - Alouch, Neil
AU - Ahmed, Arslan
AU - Jagadesh, Sunil K.
N1 - Funding Information:
The authors acknowledge the contributions of Saad Ur Rahman.
Publisher Copyright:
© Copyright © 2021 Baylor University Medical Center.
PY - 2021
Y1 - 2021
N2 - Vascular endothelial growth factor (VEGF) inhibitors are used in the treatment of various cancers as well as diabetic retinopathy. The systemic use of these drugs has been associated with adverse effects such as worsening hypertension, proteinuria, and renal function. There have been some reported cases of worsening hypertension, thrombotic microangiopathy, or glomerular disease after intravitreal injections of bevacizumab, aflibercept, and ranibizumab. We present a case of a patient who was taking intravitreal bevacizumab injections for diabetic retinopathy and was hospitalized with worsening renal function, high blood pressure, and nephrotic-range proteinuria in the setting of tight glycemic control.
AB - Vascular endothelial growth factor (VEGF) inhibitors are used in the treatment of various cancers as well as diabetic retinopathy. The systemic use of these drugs has been associated with adverse effects such as worsening hypertension, proteinuria, and renal function. There have been some reported cases of worsening hypertension, thrombotic microangiopathy, or glomerular disease after intravitreal injections of bevacizumab, aflibercept, and ranibizumab. We present a case of a patient who was taking intravitreal bevacizumab injections for diabetic retinopathy and was hospitalized with worsening renal function, high blood pressure, and nephrotic-range proteinuria in the setting of tight glycemic control.
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U2 - 10.1080/08998280.2021.1885285
DO - 10.1080/08998280.2021.1885285
M3 - Article
AN - SCOPUS:85101914032
VL - 34
SP - 527
EP - 529
JO - Baylor University Medical Center Proceedings
JF - Baylor University Medical Center Proceedings
SN - 0899-8280
IS - 4
ER -